Open Access

Erratum: African American mitochondrial DNAs often match mtDNAs found in multiple African ethnic groups

  • Bert Ely1Email author,
  • Jamie Lee Wilson2,
  • Fatimah Jackson3 and
  • Bruce A Jackson2
BMC Biology20075:13

DOI: 10.1186/1741-7007-5-13

Received: 26 March 2007

Accepted: 26 March 2007

Published: 26 March 2007

The Research article to this article has been published in BMC Biology 2006 4:34

After the publication of this work [1], we became aware that AFDIL data set used to construct our database of sub-Saharan mtDNA sequences had been mislabelled, and in fact, did not contain Sierra Leone mtDNA sequences. We have obtained the correct Sierra Leone data set from AFDIL, reconstructed the database using the new file, and reanalyzed all of the data. The size of our database was reduced from 3725 to 3717 since the new Sierra Leone data set contained 109 sequences instead of 117 in the mislabelled data set. The swapping of data sets resulted in a cascade of minor corrections to Tables 2, 3, 4, 5, and 6 (see below). We also corrected an error in the entry for BAM013 in Table 7. However, the only major change was that there were a number of matches of African-American sequences to sequences in the mislabelled data set. Thus, the number of African-American matches to single ethnic groups dropped from a total of 16 to 9 (Table 3) representing just 5% of the African American sequences that we compared to the database.
Table 2

Characteristics of the sub-Saharan mtDNA HVS-I database

Region

Region matched (%)

 

Total

Uniquea

Multipleb

West

West Central

South

Southeast

East

West

1520

35

18

23

20

0

1

2

West Central

995

35

28

16

14

0

5

2

South

127

39

15

0

0

39

7

0

Southeast

416

25

54

2

17

1

1

0

East

659

52

14

1

2

0

0

30

Total

3717

37

24

     

aHaplotypes found once or in a single ethnic group.

bHaplotypes found in ethnic groups from three or more regions.

Table 3

Number of Perfect Matches to African-American HVS-I sequences

 

Sample

Number of Matched Ethnic Groups

Gullah/Geechee

AFDIL

None

30

43

1

5

4

2–3

6

5

4–9

10

15

>9

23

30

Totals

74

97

Table 4

Imperfect matches to the Gullah/Geechee and AFDIL African-American HVS-I sequences

 

Number of sequences

Number of ethnic groups matched

Number of sequences

One mismatch

47

1

14

  

2–3

5

  

4–9

16

  

>9

12

More than 1 mismatch

26

 

ND

Table 5

Geographical source of mtDNA HVS-I matches

Number of matches

Gullah/Geechee individuals

AFDIL African American individuals

 

W. Africa

E. Africa

Both

W. Africa

E. Africa

Both

1–5

13

1

2

11

1

2

>5

4

0

24

5

0

33

Table 6

Distribution of single region matches

Sample

West

W. Central

East

Gullah/Geechee

7

5

1

AFDIL AA

2

3

1

Table 7

Mitochondrial DNA HVS-I sequences included in this study

Ethnic Group

Country

Sample Size

Reference

West Africa:

   

multiple

Senegal

50

Rando et al. 1998 [9]

Serer

Senegal

23

Rando et al. 1998 [9]

Wolof

Senegal

48

Rando et al. 1998 [9]

Mandenka

Senegal

110

Graven et al. 1995 [10] Watson et al. 1997 [11]

multiple

Guiné-Bissau

372

Rosa et al. 2004 [12]

Malinke

Mali

61

Ely et al., unpublished

Bambara

Mali

19

Ely et al., unpublished

Limba

Sierra Leone

67

Jackson et al. 2005 [3]

Loko

Sierra Leone

29

Jackson et al. 2005 [3]

Temne

Sierra Leone

121

Jackson et al. 2005 [3]

Mende

Sierra Leone

59

Jackson et al. 2005 [3]

unknown

Sierra Leone

108

Monson et al. 2002 [13]

Fulbe

Nigeria, Niger

60

Watson et al. 1997 [11]

Hausa

Nigeria, Niger

20

Watson et al. 1997 [11]

Kanuri

Nigeria, Niger

14

Watson et al. 1997 [11]

Songhai

Nigeria, Niger

10

Watson et al. 1997 [11]

Tuareg

Nigeria, Niger

23

Watson et al. 1997 [11]

Yoruba

Nigeria

33

Vigilant et al. 1991 [14]; Watson et al. 1997 [11]

unknown

Cabo Verde

292

Brehm et al. 2002 [15]

Total

 

1520

 

West Central Africa:

   

Kotoko

Cameroon

18

Černý et al. 2004 [16]

Hide

Cameroon

23

Černý et al. 2004 [16]

Masa

Cameroon

31

Černý et al. 2004 [16]

Mafa

Cameroon

32

Černý et al. 2004 [16]

Bakaka

Cameroon

50

Coia et al. 2005 [17]

Bamileke

Cameroon

48

Coia et al. 2005 [17]

Bassa

Cameroon

46

Coia et al. 2005 [17]

Daba

Cameroon

20

Coia et al. 2005 [17]

Ewondo

Cameroon

53

Coia et al. 2005 [17]

Fali

Cameroon

41

Coia et al. 2005 [17]

Fulbe

Cameroon

34

Coia et al. 2005 [17]

Mandara

Cameroon

37

Coia et al. 2005 [17]

Podokwo

Cameroon

39

Coia et al. 2005 [17]

Tali

Cameroon

20

Coia et al. 2005 [17]

Tupuri

Cameroon

25

Coia et al. 2005 [17]

Uldeme

Cameroon

28

Coia et al. 2005 [17]

Biaka

Central African Republic

17

Vigilant et al. 1991 [14] Watson et al. 1997 [11]

Mbenzele-Pygmy

Central African Republic

57

Destro-Bisol et al. 2004 [18]

Angolares

São Tomé and Príncipe

30

Trovoada et al. 2004 [19]

Forros

São Tomé and Príncipe

35

Trovoada et al. 2004 [19]

Tongas

São Tomé and Príncipe

38

Trovoada et al. 2004 [19]

unknown

São Tomé and Príncipe

50

Mateu et al. 1997 [20]

Bubi

Equatorial Guinea

45

Mateu et al. 1997 [20]

Fang

Equatorial Guinea

11

Pinto et al. 1996 [21]

Mbuti

Democratic Republic of Congo

13

Vigilant et al. 1991 [14] Watson et al. 1997 [11]

Bantu-speaking

Cabinda

110

Beleza et al. 2005 [4]

Mbundu

Angola

44

Plaza et al. 2004 [22]

Total

 

995

 

East Africa:

   

Nuer

South Sudan

11

Krings et al. 1999 [23]

Dinka

South Sudan

47

Krings et al. 1999 [23]

Shilluk

South Sudan

7

Krings et al. 1999 [23]

multiple

Ethiopia

21

Kivisild et al. 2004 [24]

Tigrais

Ethiopia, Eritrea

53

Kivisild et al. 2004 [24]

Gurage

Ethiopia

21

Kivisild et al. 2004 [24]

Afar

Ethiopia

16

Kivisild et al. 2004 [24]

Amhara

Ethiopia

120

Kivisild et al. 2004 [24]

Amhara

Ethiopia

7

Quintana-Murci et al. 1999 [25]

Oromo

Ethiopia

33

Kivisild et al. 2004 [24]

Oromo

Kenya, Ethiopia

18

Quintana-Murci et al. 1999 [25]

unknown

Kenya

100

Brandstätter et al. 2004 [26]

Kikuyu

Kenya

24

Watson et al. 1997 [11]

Turkana

Kenya

37

Watson et al. 1997 [11]

Somali

Kenya, Somalia, Ethiopia

27

Watson et al. 1997 [11]

Hadza

Tanzania

17

Vigilant et al. 1991 [14]

Hadza

Tanzania

49

Knight et al. 2003 [27]

Dakota

Tanzania

18

Knight et al. 2003 [27]

Iraqw

Tanzania

12

Knight et al. 2003 [27]

Sukuma

Tanzania

21

Knight et al. 2003 [27]

Total

 

659

 

Southeast Africa:

   

mulitple

Mozambique

109

Pereira et al. 2001 [6]

multiple

Mozambique

307

Salas et al. 2002 [5]

Total

 

416

 

South Africa:

   

!Kung

Botswana

34

Vigilant et al. 1991 [14]

!Kung

South Africa

43

Chen et al. 2000 [28]

Khwe

South Africa

31

Chen et al. 2000 [28]

Herero

Bostwana, Namibia

19

Vigilant et al. 1991 [14]

Total

 

127

 
Table 8

Malinke and Bambara Mitochondrial DNA HVS-I sequences included in this study

ID

Ethnicity

Haplogroup

Hvs-I polymorphisms a

BAM676

Bambara

L1b

126 187 189 223 264 270 278 311

BAM612

Bambara

L1b1

126 187 189 223 256 264 270 278 293 311

BAM595

Bambara

L1b1

126 187 189 223 264 266 270 278 293 311

BAM599

Bambara

L1b1

126 187 189 223 264 266 270 278 293 311

BAM600-2

Bambara

L1b1

126 187 189 223 264 270 278 293 311

BAM060

Bambara

L2a

223 278 294 368 390

BAM598

Bambara

L2a1

189 192 209 223 278 294 309 390

BAM604

Bambara

L2a1a

223 278 286 294 309 390

BAM627

Bambara

L2b

114A 213 223 278 290 355 390

BAM659

Bambara

L2b1

114A 129 213 223 278 362 390

BAM037

Bambara

L2c

129 223 261 278 390

BAM685

Bambara

L2c2

183 223 264 278 320 390

BAM679-1

Bambara

L2c2

223 264 278 390

BAM629

Bambara

L2d2

111A 145 184 223 239 278 292 355 390 399 400

BAM068

Bambara

L3b

124 223 278 362

BAM072

Bambara

L3e2

223 284 320

BAM605

Bambara

L3e3

093 148 223 265 311

BAM027

Bambara

L3f1

049 129 209 223 292 295 311

BAM614

Bambara

L3f1

223 272 292 311

BAM 552

Malinke

L1b

111 126 187 189 223 239 270 278 311

BAM 237

Malinke

L1b

126 187 189 223 239 264 270 278 311

BAM 357

Malinke

L1b

126 187 189 223 239 264 270 278 311

BAM 040

Malinke

L1b

126 187 189 223 264 270 278 311

BAM 385

Malinke

L1b1

093 126 145 187 189 223 264 270 278 293 311

BAM 555

Malinke

L1b1

126 187 189 213 223 260 264 270 278 293 311

BAM 225

Malinke

L1b1

126 187 189 223 264 270 278 293 311 362 400

BAM 407

Malinke

L1c

129 189 215 223 278 294 311 360

BAM 013

Malinke

L2a

189 223 278 390

BAM 397

Malinke

L2a

189 192 223 278 294 390

BAM 221

Malinke

L2a

189 223 278 294 390

BAM 426

Malinke

L2a

223 278 286 294 390

BAM 083

Malinke

L2a

223 278 294 390

BAM 414

Malinke

L2a1

093 189 192 223 265 278 294 309 390

BAM 143

Malinke

L2a1

086 223 230 278 294 309 390

BAM 117

Malinke

L2a1

092 223 278 294 309 390

BAM 341

Malinke

L2a1

093 223 278 294 309 390

BAM 534

Malinke

L2a1

140 189 192 223 278 294 309 390

BAM 665

Malinke

L2a1

189 192 223 266 278 294 309 390

BAM 082

Malinke

L2a1

189 192 223 278 294 309

BAM 174

Malinke

L2a1

192 223 278 294 309 390

BAM 195

Malinke

L2a1

192 223 278 294 309 390

BAM 395

Malinke

L2a1

223 278 294 309 368 390

BAM 406

Malinke

L2a1

223 278 294 309 390

BAM 204

Malinke

L2a1

223 278 309 390

BAM 296

Malinke

L2b1

056 114A 129 213 223 278 362 390

BAM 085

Malinke

L2b1

093 114A 129 213 223 278 355 362 390

BAM 577

Malinke

L2b1

114A 129 213 223 278 311 355 362 390

BAM 290

Malinke

L2b1

114A 129 213 223 278 362 390

BAM 319

Malinke

L2b1

114A 129 213 223 278 362 390

BAM 401

Malinke

L2c

129 223 261 278 362 390

Notes

Authors’ Affiliations

(1)
Department of Biological Sciences, University of South Carolina
(2)
Biomedical Engineering and Biotechnology Program, University of Massachusetts
(3)
Department of Anthropology, University of Maryland

References

  1. Ely B, Wilson JL, Jackson F, Jackson BA: African American mitochondrial DNAs often match mtDNAs found in multiple African ethnic groups. BMC Biology. 2006, 4: 34-10.1186/1741-7007-4-34.PubMed CentralView ArticlePubMed

Copyright

© Ely et al; licensee BioMed Central Ltd. 2007

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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