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Protein aggregates in natural and synthetic biology

Mo Khalil, Giulio Chiesa and Szilvia Kiriakov discuss protein aggregates in biology, and how self-assembling systems can be harnessed for the purposeful manipulation of biological function.

Mapping the live brain

Ryo Yoshida, Yuichi Iino and colleagues annotated neuronal identities in live C. elegans, creating a dataset of their expression patterns and positions to allow automated identification of neurons during live imaging.

Chromosomal diversity in Aedes aegypti

Seth Redmond and colleagues characterize chromosomal diversity in subspecies of Aedes aegypti, creating a library of genomic rearrangements as an important resource for genetic studies of this mosquito vector.

Introducing our Research Synthesis Series

In their inaugural Editorial, our Guest Editors Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod, and Wolfgang Viechtbauer discuss how meta-analyses and other research synthesis methodologies support research, and the benefits of embracing them across biological disciplines.

Pervasive contamination in bacterial WGS datasets

New research from Galo Goig and colleagues finds that short-read contaminants are pervasive in bacterial whole-genome sequencing datasets, and that they can introduce large biases in variant analyses.

Call for papers: Research Synthesis and Meta-research in Biology

We’re inviting submissions to our new Series guest edited by Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod and Wolfgang Viechtbauer.

Featured Editorial

Introducing our series: research synthesis and meta-research in biology

Shinichi Nakagawa, Julia Koricheva, Malcolm Macleod & Wolfgang Viechtbauer

Published 05 March 2020


Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
Gillian P. McHugo et al.
Published 02 December 2019

Are we there yet? The long walk towards the development of efficient symbiotic associations between nitrogen-fixing bacteria and non-leguminous crops
Vânia C. S. Pankievicz et al.
Published 03 December 2019

The microbiome of the upper respiratory tract in health and disease
Christina Kumpitsch, Kaisa Koskinen, Veronika Schöpf & Christine Moissl-Eichinger
Published: 07 November 2019

The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health
Jillian L. Waters & Ruth E. Ley
Published: 28 October 2019

Studying the gut virome in the metagenomic era: challenges and perspectives
Sanzhima Garmaeva, Trishla Sinha, Alexander Kurilshikov, Jingyuan Fu, Cisca Wijmenga & Alexandra Zhernakova
Published: 28 October 2019

  1. Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

    Content type: Research article

Focus: Pathogens

Read the latest papers on pathogenic organisms and disease across BMC flagship journals.

Population-level mathematical modeling of antimicrobial resistance: a systematic review
Anna Maria Niewiadomska et al.

Published in BMC Medicine 24 April 2019

A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk​​​​​​​
Elvire Berthenet et al.

Published in BMC Biology 02 August 2018

INSaFLU: an automated open web-based bioinformatics suite “from-reads” for influenza whole-genome-sequencing-based surveillance​​​​​​​
Vítor Borges et al.

Published in Genome Medicine 29 June 2018

HOPS: automated detection and authentication of pathogen DNA in archaeological remains​​​​​​​
Ron Hübler et al.
Published in Genome Biology 16 December 2019

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Announcement: COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.