TbAGO1-/- cells are resistant to RNAi. A. FACS profile of TbAGO1-/- (KO), or of TbAGO1-/- +GFP::TbAGO1
Ticells grown in the absence (-TET, non-induced, thin green lines) or in the presence of tetracycline (+TET, induced, thick green lines). B. The indicated cell lines were transfected with PFRA dsRNA and returned to culture for 15 h before fixation and monitoring of the RNAi phenotype by immunofluorescence.