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Table 1 Proportion of various aberrant cell types.

From: TbAGO1, an Argonaute protein required for RNA interference, is involved in mitosis and chromosome segregation in Trypanosoma brucei

 

Mitotic cells without spindle1 (%)

Abnormal spindles2 (%)

Unequal distribution of nucleolar marker3 (%)

W.T.

3.2

0.0

8.2

K.O.

21.0

43.9

33.0

K.O. + GFP::TbAGO1

13.6

16.7

18.0

  1. 12K1N cells were scored for the presence or the absence of a recognisable mitotic spindle after KMX-1 staining, n > 118. 2In cells with recognisable spindle, n > 118 3Binucleated cells were scored, n > 100
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BMC Biology

ISSN: 1741-7007

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