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Table 1 Proportion of various aberrant cell types.

From: TbAGO1, an Argonaute protein required for RNA interference, is involved in mitosis and chromosome segregation in Trypanosoma brucei

  Mitotic cells without spindle1 (%) Abnormal spindles2 (%) Unequal distribution of nucleolar marker3 (%)
W.T. 3.2 0.0 8.2
K.O. 21.0 43.9 33.0
K.O. + GFP::TbAGO1 13.6 16.7 18.0
  1. 12K1N cells were scored for the presence or the absence of a recognisable mitotic spindle after KMX-1 staining, n > 118. 2In cells with recognisable spindle, n > 118 3Binucleated cells were scored, n > 100
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BMC Biology

ISSN: 1741-7007

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