|
Cell line
|
Tumor type
|
Three-dimensional morphology
|
Supplier
|
Medium
|
|---|
|
U-87 MG
|
GBM (adult)
|
T
|
ATCC
|
1
|
|
A172
|
GBM (adult)
|
T
|
ATCC
|
1
|
|
SF126
|
GBM (adult)
|
T
|
JCRB
|
1
|
|
LN-229
|
GBM (adult)
|
T
|
ATCC
|
1
|
|
SF268
|
GBM (adult)
|
C
|
NCI repository
|
1
|
|
SF188
|
GBM (pediatric)
|
T
|
Bax, 2009 [56]
|
2
|
|
KNS42
|
GBM (pediatric)
|
T
|
Bax, 2009 [56]
|
2
|
|
RES186
|
Astrocytoma (pediatric)
|
T
|
Bax, 2009 [56]
|
2
|
|
RES259
|
Astrocytoma (pediatric)
|
T
|
Bax, 2009 [56]
|
2
|
|
UW479
|
Astrocytoma (pediatric)
|
L
|
Bax, 2009 [56]
|
2
|
|
WT-CLS1
|
Wilm's kidney
|
T
|
CRUK Cell Line Services
|
1
|
|
WiT49
|
Wilm's kidney
|
T
|
Dr H Yeger, Hospital for Sick Children, Toronto
|
1
|
|
IMR-32
|
Neuroblastoma
|
T
|
ATCC
|
1
|
|
SH-SY5Y
|
Neuroblastoma
|
C
|
Dr L Chesler, ICR
|
3
|
|
KELLY
|
Neuroblastoma
|
C
|
Dr L Chesler, ICR
|
3
|
|
SHEP
|
Neuroblastoma
|
T
|
Dr L Chesler, ICR
|
3
|
|
U-2 0S
|
Osteosarcoma
|
C
|
ATCC
|
1
|
|
Detroit 562
|
SCC (pharynx)
|
T
|
ATCC
|
1
|
|
CAL 27
|
SCC (tongue)
|
T
|
ATCC
|
1
|
|
PECA/CA-PJ34
|
SCC (basaloid)
|
T
|
ECACC
|
4
|
|
PE/CA-PJ41a
|
SCC (oral)
|
C
|
ECACC
|
4
|
|
SIHN-011A
|
SCC (tongue)
|
C
|
O-charoenrat, 2001 [57]
|
1
|
|
LICR-LON-HN4
|
SCC (larynx)
|
T
|
Easty, 1981 [58]
|
1
|
|
SK-Mel-5
|
Melanoma
|
L
|
ATCC
|
1
|
|
NCI-H23
|
Lung
|
C
|
ATCC
|
3
|
|
MDA-MB-231a
|
Breast
|
C
|
ATCC
|
1
|
|
MCF-7
|
Breast
|
C
|
ATCC
|
1
|
|
DLD-1
|
Colon
|
T
|
ATCC
|
1
|
|
HCT 116
|
Colon
|
T
|
ATCC
|
1
|
|
RKOa
|
Colon
|
L
|
ATCC
|
1
|
|
HT-29
|
Colon
|
T
|
ATCC
|
1
|
|
SW620a
|
Colon
|
L
|
ATCC
|
1
|
|
PC-3a
|
Prostate
|
L
|
ATCC
|
3
|
|
A2780
|
Ovarian
|
L
|
ECACC
|
3
|
|
IGROV-1a
|
Ovarian
|
L
|
CRUK Cell Line Services
|
3
|
|
SK-OV-3a
|
Ovarian
|
L
|
ATCC
|
3
|
|
PANC-1a
|
Pancreatic
|
C
|
ATCC
|
1
|
|
MIA PaCa-2
|
Pancreatic
|
L
|
ATCC
|
1
|
|
Hep G2
|
Hepatocellular
|
C
|
ATCC
|
5
|
|
Hep 3B
|
Hepatocellular
|
C
|
ATCC
|
5
|
- aCell lines in which three-dimensional structure is improved by addition of Matrigel at spheroid initiation.
- Medium: 1 = DMEM; 2 = DMEM:F12; 3 = RPMI; 4 = Iscove's Modified Dulbecco's Medium; 5 = Eagle's Minimum Essential Medium.
- ATCC = American Type Culture Collection; C = compact aggregate; ECACC = European Collection of Cell Cultures; GBM = glioblastoma; JCRB = Japanese Collection of Research Bioresources; L = loose aggregate; SCC = squamous cell carcinoma; T = tight spheroid
