Figure 7From: UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulationUBXN7 docks on neddylated cullins using its UIM motif. Each domain in UBXN7 mediates a specific interaction: the UBA domain interacts with ubiquitylated HIF1α, the UIM motif anchors the neddylated CRL complex and the UBX domain recruits the p97/NPL4/UFD1 complex.Back to article page