Table 2 GO enrichment for the different groups of genes identified in the transcriptome and translatome comparison
GO term | Genes in GO term | Group | Genes in group | P-value | In group and term |
|---|---|---|---|---|---|
Response to oxidative stress | 83 | ++ | 142 | 6.1·10-9 | 14 |
Response to stress | 813 | ++ | 142 | 7.9·10-18 | 60 |
Protein unfolding | 3 | ++ | 142 | 0.002 | 2 |
Protein refolding | 17 | ++ | 142 | 0.0006 | 4 |
Protein folding | 113 | ++ | 142 | 0.0003 | 10 |
Ribosome biogenesis | 355 | -- | 138 | 2.5·10-67 | 83 |
Ribosomal large subunit biogenesis | 73 | -- | 138 | 5.3·10-26 | 27 |
Ribosomal small subunit biogenesis | 52 | -- | 138 | 1.4·10-15 | 17 |
Ribosome assembly | 69 | -- | 138 | 7.7·10-24 | 25 |
Ribosomal large subunit assembly | 39 | -- | 138 | 2.8·10-12 | 13 |
Ribosomal small subunit assembly | 16 | -- | 138 | 1.2·20-6 | 6 |
Ribosome localization | 43 | -- | 138 | 3.5·10-9 | 11 |
Translation | 721 | -- | 138 | 4.0·10-11 | 47 |
Regulation of translation | 190 | -- | 138 | 3.8·10-9 | 21 |
Regulation of translational fidelity | 15 | -- | 138 | 5.0·10-2 | 2 |
Response to drug | 120 | +- | 88 | 0.09 | 3 |
Drug transport | 20 | +- | 88 | 0.0007 | 3 |
Multidrug transport | 11 | +- | 88 | 0.0001 | 3 |
Response to toxin | 31 | +- | 88 | 0.002 | 3 |
Response to chemical stimulus | 457 | +- | 88 | 0.02 | 9 |
Transposition, RNA mediated | 71 | +- | 88 | 9.0·10-9 | 9 |
Transposition | 74 | +- | 88 | 1.3·10-8 | 9 |