TY - JOUR AU - Virk, Bhupinder AU - Correia, Gonçalo AU - Dixon, David P. AU - Feyst, Inna AU - Jia, Jie AU - Oberleitner, Nikolin AU - Briggs, Zoe AU - Hodge, Emily AU - Edwards, Robert AU - Ward, John AU - Gems, David AU - Weinkove, David PY - 2012 DA - 2012/07/31 TI - Excessive folate synthesis limits lifespan in the C. elegans: E. coliaging model JO - BMC Biology SP - 67 VL - 10 IS - 1 AB - Gut microbes influence animal health and thus, are potential targets for interventions that slow aging. Live E. coli provides the nematode worm Caenorhabditis elegans with vital micronutrients, such as folates that cannot be synthesized by animals. However, the microbe also limits C. elegans lifespan. Understanding these interactions may shed light on how intestinal microbes influence mammalian aging. SN - 1741-7007 UR - https://doi.org/10.1186/1741-7007-10-67 DO - 10.1186/1741-7007-10-67 ID - Virk2012 ER -