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Table 1 Percentage of genes with signal peptides or transmembrane domains

From: Frequency of intron loss correlates with processed pseudogene abundance: a novel strategy to test the reverse transcriptase model of intron loss

 

n

Absence of signal peptides

P

Absence of transmembrane domains

P

Rats

     

IL genes

65

92.3%

0.003

93.8%

6 × 10-4

NIL genes

8,410

75.7%

 

74.6%

 

Parental genes

637

93.4%

< 10-16

90.1%

< 10-16

Other genes

7,838

74.4%

 

73.6%

 

Mice

     

IL genes

42

95.2%

0.004

92.9%

0.015

NIL genes

8,410

74.6%

 

75.5%

 

Parental genes

1,013

91.3%

< 10-16

88.3%

< 10-16

Other genes

7,439

72.5%

 

73.9%

 
  1. Absence of a signal peptide or a transmembrane domain indicates mRNA translation on free cytoplasmic ribosomes. Pearson's chi-square test was used to calculate the P values. IL: intron-lost; NIL: no-intron-lost genes; Parental genes: parental genes of processed pseudogenes.