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Table 1 Percentage of genes with signal peptides or transmembrane domains

From: Frequency of intron loss correlates with processed pseudogene abundance: a novel strategy to test the reverse transcriptase model of intron loss

  n Absence of signal peptides P Absence of transmembrane domains P
Rats      
IL genes 65 92.3% 0.003 93.8% 6 × 10-4
NIL genes 8,410 75.7%   74.6%  
Parental genes 637 93.4% < 10-16 90.1% < 10-16
Other genes 7,838 74.4%   73.6%  
Mice      
IL genes 42 95.2% 0.004 92.9% 0.015
NIL genes 8,410 74.6%   75.5%  
Parental genes 1,013 91.3% < 10-16 88.3% < 10-16
Other genes 7,439 72.5%   73.9%  
  1. Absence of a signal peptide or a transmembrane domain indicates mRNA translation on free cytoplasmic ribosomes. Pearson's chi-square test was used to calculate the P values. IL: intron-lost; NIL: no-intron-lost genes; Parental genes: parental genes of processed pseudogenes.