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Figure 1 | BMC Biology

Figure 1

From: Copy-number variation of cancer-gene orthologs is sufficient to induce cancer-like symptoms in Saccharomyces cerevisiae

Figure 1

Haploproficient genes. The incidence of genes identified in genome-wide deletion library screens [8] as haploproficient within the S.cerevisiae cell cycle (haploproficient genes highlighted in red) (pathway diagram derived from the KEGG database [45]). Abbreviations: APC = anaphase promoting complex; SCF = Sck1-Cdc53/CUL-F Box receptor E3 complex; MCM = minichromosome maintenance complex; ORC = origin recognition complex; PP2A = protein phosphatase 2 complex. Haploproficient members of the complexes are listed in Additional file 2: Table S2.

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