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Figure 2 | BMC Biology

Figure 2

From: Copy-number variation of cancer-gene orthologs is sufficient to induce cancer-like symptoms in Saccharomyces cerevisiae

Figure 2

Interrelationships of drug-response profiles of yeast deletion mutants. Left panel: Hierarchical clustering of the response of the heterozygous and homozygous deletion mutants of the HPGI set to treatment with a panel of anti-cancer compounds. Right panel: Comparison of the drug-response profiles for the heterozygous and homozygous mutants of those HPGI genes for which cancer drug sensitivity differs markedly according to gene copy number.

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