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Table 4 Two-way permutational multivariate analysis of variance (PERMANOVA) results comparing muscle mRNA levels between cold-acclimated and warm-acclimated normal thyroid and hypothyroid fish

From: Thyroid hormone actions are temperature-specific and regulate thermal acclimation in zebrafish (Danio rerio)

 

Acclimation temperature

Thyroid status

Acclimation temperature × Thyroid Status

Gene

F

d.f.

P

F

d.f.

P

F

d.f.

P

PGC1α

3.330

1, 34

0.041*

6.454

1, 34

0.001**

4.357

1, 34

0.026*

PGC1β

12.690

1, 34

0.001**

2.677

1, 34

0.09

2.068

1, 34

0.108

PPARδ

5.708

1, 31

0.010*

0.172

1, 31

0.827

2.511

1, 31

0.117

NRF1

5.069

1, 28

0.021*

0.921

1, 28

0.343

0.268

1, 28

0.714

NRF2a

1.434

1, 28

0.239

0.145

1, 28

0.885

1.086

1, 28

0.302

NRF2b

4.108

1, 17

0.045*

0.557

1, 17

0.537

0.060

1, 17

0.948

COX Vb2

1.996

1, 33

0.124

3.786

1, 33

0.029*

7.293

1, 33

0.002**

ATPase A

3.612

1, 27

0.048*

2.260

1, 27

0.099

3.136

1, 27

0.043*

ATPase B

1.948

1, 27

0.148

1.216

1, 27

0.269

5.903

1, 27

0.012*

COX II

12.410

1, 25

0.001**

3.850

1, 25

0.026*

2.478

1, 25

0.079

ATP 8/6

7.221

1, 24

0.004**

8.229

1, 24

0.002**

2.631

1, 24

0.068

  1. Abbreviations: ATPase A, F0F1-ATPase subunit A; ATPase B, F0F1-ATPase subunit B; ATPase 8/6, F0F1-ATPase subunits 8 and 6; COX II, Cytochrome c oxidase subunit 2; COX Vb2, cytochrome c oxidase subunit 5b2; d.f. degrees of freedom; NRF1, Nuclear respiratory factor 1; NRF2a, Nuclear respiratory factor 2a; NRF2b, Nuclear respiratory factor 2b; PGC1α, Peroxisome proliferator-activated receptor γ coactivator 1-α; PGC1β, Peroxisome proliferator-activated receptor γ coactivator 1-β; PPARδ, Peroxisome proliferator-activated receptor δa and δb.
  2. *P<0.05.
  3. **P<0.01.