Table 5 Two-way permutational multivariate analysis of variance (PERMANOVA) results comparing liver mRNA levels between cold-acclimated and warm-acclimated normal thyroid and hypothyroid fish

PGC1α

13.672

1, 32

0.001**

2.597

1, 32

0.095

1.521

1, 32

0.238

PGC1β

26.692

1, 29

0.001**

1.191

1, 29

0.274

6.374

1, 29

0.011*

PPARδ

25.657

1, 31

0.001**

1.128

1, 31

0.324

6.139

1, 31

0.010*

NRF1

32.817

1, 26

0.001**

0.784

1, 26

0.400

3.464

1, 26

0.050*

NRF2a

7.869

1, 22

0.004**

1.163

1, 22

0.290

5.015

1, 22

0.020*

NRF2b

15.085

1, 24

0.001**

0.578

1, 24

0.497

6.708

1, 24

0.017*

COX Vb2

9.789

1, 20

0.005**

3.490

1, 20

0.049*

0.336

1, 20

0.672

ATPase A

23.119

1, 32

0.001**

0.292

1, 32

0.713

1.109

1, 32

0.308

ATPase B

6.456

1, 33

0.007**

0.097

1, 33

0.942

1.604

1, 33

0.189

COX II

6.458

1, 22

0.007**

1.240

1, 22

0.295

6.377

1, 22

0.013*

ATP 8/6

4.056

1, 21

0.06

0.422

1, 21

0.571

3.904

1, 21

0.044*