Skip to main content

Table 1 Analysis of host gene expression in the colonic epithelium

From: Bacteroides thetaiotaomicron and Faecalibacterium prausnitziiinfluence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent

 

GF

Bt-2d

Bt-30d

Bt + Fp-30d

muc2

1.04 ± 0.05 a

1.52 ± 0.10 a,b

1.71 ± 0.10 b

1.79 ± 0.22 b

muc4

1.00 ± 0.05 a

3.51 ± 0.33 b

2.69 ± 0.29 a,b

2.83 ± 0.43 b

klf4

1.01 ± 0.05 a

1.30 ± 0.10 b

1.09 ± 0.04 a,b

1.08 ± 0.09 a,b

c1galt1

1.00 ± 0.03 a

2.28 ± 0.26 b

1.23 ± 0.16 a

1.54 ± 0.24 a,b

b4galt4

1.02 ± 0.11 a

3.89 ± 0.42 b

2.13 ± 0.20 a,c

3.00 ± 0.39 b,c

st3gal4

1.05 ± 0.14 a

2.98 ± 0.37 b

1.39 ± 0.16 a

1.67 ± 0.22 a

st6galnac3

1.07 ± 0.27 a

0.80 ± 0.29 a

1,11 ± 0.55 a

0.41 ± 0.11 a

gal3st3

n.d.

n.d.

n.d.

n.d.

chst7

1.17 ± 0.36 a

1.84 ± 0.55 a

1.02 ± 0.23 a

0.77 ± 0.20 a

  1. Relative abundance of muc2, muc4, klf4, c1galt1, b4galt4, st3gal4, st6galnac3, gal3st3 and chst7 mRNAs in germfree (GF) (n = 4 to 10), Bt-2d (n = 4), Bt-30d (n = 6) and Bt + Fp-30d (n = 6). Means with different letters (a, b, c) are significantly different (P-value <0.05); n.d., not detected.