Table 2 Distribution of virulence-related factors among K. pneumoniae genomes analyzed
Virulence-factor | SB3341 | SB2390 | SB3193 | NTUH | MGH | Functional role |
|---|---|---|---|---|---|---|
rmpA | ++ | - | - | ++ | - | Regulator of capsule expression |
Aerobactin | + | - | - | + | - | Siderophore |
Enterobactin | + | + | + | + | + | Siderophore |
Yersiniabactin | + | + | + | + | - | Siderophore |
Colibactin | + | - | - | - | - | Genotoxin |
T4SS (virB) | + | + | - | + | - | Conjugative machinery/protein secretion |
T2SS | + | + | + | + | + | Protein secretion |
T6SS | + | + | + | + | + | Protein secretion |
Pld-family | + | - | - | - | - | Lipid metabolism |
Sel1 lipoproteins | + | - | - | - | - | Unknown |
cOMP | + | - | - | - | - | Putative cytotoxin |
Igg-like | + | - | - | - | - | Binding to extra cellular matrix compounds |
SEFIR-domain | + | - | - | - | - | Potentially hijack IL17R signaling pathways |
Bcl | + | + | - | + | + | Binding to hydrophobic ligands / putative regulation of homeostasis and immunity |