TY - JOUR AU - Xie, Gary AU - Bonner, Carol A. AU - Song, Jian AU - Keyhani, Nemat O. AU - Jensen, Roy A. PY - 2004 DA - 2004/06/23 TI - Inter-genomic displacement via lateral gene transfer of bacterial trp operons in an overall context of vertical genealogy JO - BMC Biology SP - 15 VL - 2 IS - 1 AB - The growing conviction that lateral gene transfer plays a significant role in prokaryote genealogy opens up a need for comprehensive evaluations of gene-enzyme systems on a case-by-case basis. Genes of tryptophan biosynthesis are frequently organized as whole-pathway operons, an attribute that is expected to facilitate multi-gene transfer in a single step. We have asked whether events of lateral gene transfer are sufficient to have obscured our ability to track the vertical genealogy that underpins tryptophan biosynthesis. SN - 1741-7007 UR - https://doi.org/10.1186/1741-7007-2-15 DO - 10.1186/1741-7007-2-15 ID - Xie2004 ER -