SesA and SesB conservation during evolution. (A) Alignment of SesAp with its homologues in Fusarium graminearum (F. gra 214 and F. gra 201) and Podospora anserina (P. ans). The amino acid change in s
1 is boxed. (B) Alignment of SesBp with representative homologues from F. graminearum (Fg1 and Fg2; the sequence was obtained from the Fungal Genome Initiative, http://www-genome.wi.mit.edu), P. anserina (Pa; http://podospora.igmors.u-psud.fr), Homo sapiens (Hs; GENBANK: BC001705), Drosophila melanogaster (Dm; GENBANK: AAF5369), and Caenorhabditis elegans (Ce; PIR: T21079). Arrowheads indicate the amino acid changed in s*4, s*789, and s*18; arrow indicates the position of the frameshift in s*27. (C) Conservation of Ses organization in F. graminearum. SesA corresponds to F. gra 214 of (A) and SesB corresponds to Fg1 of (B). Percentages of identity with Nectriahaematococca SesAp and SesBp are 41% and 79%, respectively. In (A) and (B), conserved amino acids are shaded. Color reflects the degree of conservation.