TY - JOUR AU - Schlunzen, F. AU - Zarivach, R. AU - Harms, J. AU - Bashan, A. AU - Tocilj, A. AU - Albrecht, R. AU - Yonath, A. AU - Franceschi, F. PY - 2001 DA - 2001// TI - Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria JO - Nature VL - 413 UR - https://doi.org/10.1038/35101544 DO - 10.1038/35101544 ID - Schlunzen2001 ER - TY - JOUR AU - Hansen, J. L. AU - Ippolito, J. A. AU - Ban, N. AU - Nissen, P. AU - Moore, P. B. AU - Steitz, T. A. PY - 2002 DA - 2002// TI - The structures of four macrolide antibiotics bound to the large ribosomal subunit JO - Mol Cell VL - 10 UR - https://doi.org/10.1016/S1097-2765(02)00570-1 DO - 10.1016/S1097-2765(02)00570-1 ID - Hansen2002 ER - TY - JOUR AU - Schlunzen, F. AU - Harms, J. M. AU - Franceschi, F. AU - Hansen, H. A. AU - Bartels, H. AU - Zarivach, R. AU - Yonath, A. PY - 2003 DA - 2003// TI - Structural basis for the antibiotic activity of ketolides and azalides JO - Structure (Camb) VL - 11 UR - https://doi.org/10.1016/S0969-2126(03)00022-4 DO - 10.1016/S0969-2126(03)00022-4 ID - Schlunzen2003 ER - TY - JOUR AU - Hansen, J. L. AU - Moore, P. B. AU - Steitz, T. A. PY - 2003 DA - 2003// TI - Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit JO - J Mol Biol VL - 330 UR - https://doi.org/10.1016/S0022-2836(03)00668-5 DO - 10.1016/S0022-2836(03)00668-5 ID - Hansen2003 ER - TY - JOUR AU - Cocito, C. AU - Di Giambattista, M. AU - Nyssen, E. AU - Vannuffel, P. PY - 1997 DA - 1997// TI - Inhibition of protein synthesis by streptogramins and related antibiotics JO - J Antimicrob Chemother VL - 39 Suppl A UR - https://doi.org/10.1093/jac/39.suppl_1.7 DO - 10.1093/jac/39.suppl_1.7 ID - Cocito1997 ER - TY - JOUR AU - Allignet, J. AU - Aubert, S. AU - Morvan, A. AU - el Solh, N. PY - 1996 DA - 1996// TI - Distribution of genes encoding resistance to streptogramin A and related compounds among staphylococci resistant to these antibiotics JO - Antimicrob Agents Chemother VL - 40 ID - Allignet1996 ER - TY - JOUR AU - Malbruny, B. AU - Canu, A. AU - Bozdogan, B. AU - Fantin, B. AU - Zarrouk, V. AU - Dutka-Malen, S. AU - Feger, C. AU - Leclercq, R. PY - 2002 DA - 2002// TI - Resistance to quinupristin-dalfopristin due to mutation of L22 ribosomal protein in Staphylococcus aureus JO - Antimicrob Agents Chemother VL - 46 UR - https://doi.org/10.1128/AAC.46.7.2200-2207.2002 DO - 10.1128/AAC.46.7.2200-2207.2002 ID - Malbruny2002 ER - TY - JOUR AU - Chinali, G. AU - Moureau, P. AU - Cocito, C. G. PY - 1984 DA - 1984// TI - The action of virginiamycin M on the acceptor, donor, and catalytic sites of peptidyltransferase JO - J Biol Chem VL - 259 ID - Chinali1984 ER - TY - JOUR AU - Nyssen, E. AU - Di Giambattista, M. AU - Cocito, C. PY - 1989 DA - 1989// TI - Analysis of the reversible binding of virginiamycin M to ribosome and particle functions after removal of the antibiotic JO - Biochim Biophys Acta VL - 1009 UR - https://doi.org/10.1016/0167-4781(89)90076-6 DO - 10.1016/0167-4781(89)90076-6 ID - Nyssen1989 ER - TY - JOUR AU - Parfait, R. AU - Cocito, C. PY - 1980 DA - 1980// TI - Lasting damage to bacterial ribosomes by reversibly bound virginiamycin M JO - Proc Natl Acad Sci U S A VL - 77 UR - https://doi.org/10.1073/pnas.77.9.5492 DO - 10.1073/pnas.77.9.5492 ID - Parfait1980 ER - TY - JOUR AU - Canu, A. AU - Leclercq, R. PY - 2001 DA - 2001// TI - Overcoming bacterial resistance by dual target inhibition: the case of streptogramins JO - Curr Drug Targets Infect Disord VL - 1 UR - https://doi.org/10.2174/1568005014606152 DO - 10.2174/1568005014606152 ID - Canu2001 ER - TY - JOUR AU - Vannuffel, P. AU - Cocito, C. PY - 1996 DA - 1996// TI - Mechanism of action of streptogramins and macrolides JO - Drugs VL - 51 Suppl 1 UR - https://doi.org/10.2165/00003495-199600511-00006 DO - 10.2165/00003495-199600511-00006 ID - Vannuffel1996 ER - TY - JOUR AU - Wang, G. AU - Taylor, D. E. PY - 1998 DA - 1998// TI - Site-specific mutations in the 23S rRNA gene of Helicobacter pylori confer two types of resistance to macrolide-lincosamide-streptogramin B antibiotics JO - Antimicrob Agents Chemother VL - 42 ID - Wang1998 ER - TY - JOUR AU - Vester, B. AU - Douthwaite, S. PY - 1994 DA - 1994// TI - Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase JO - J Bacteriol VL - 176 ID - Vester1994 ER - TY - JOUR AU - Vannuffel, P. AU - Di Giambattista, M. AU - Morgan, E. A. AU - Cocito, C. PY - 1992 DA - 1992// TI - Identification of a single base change in ribosomal RNA leading to erythromycin resistance JO - J Biol Chem VL - 267 ID - Vannuffel1992 ER - TY - JOUR AU - Vannuffel, P. AU - Di Giambattista, M. AU - Cocito, C. PY - 1994 DA - 1994// TI - Chemical probing of a virginiamycin M-promoted conformational change of the peptidyl-transferase domain JO - Nucleic Acids Res VL - 22 UR - https://doi.org/10.1093/nar/22.21.4449 DO - 10.1093/nar/22.21.4449 ID - Vannuffel1994 ER - TY - JOUR AU - Vannuffel, P. AU - Di Giambattista, M. AU - Cocito, C. PY - 1992 DA - 1992// TI - The role of rRNA bases in the interaction of peptidyltransferase inhibitors with bacterial ribosomes JO - J Biol Chem VL - 267 ID - Vannuffel1992 ER - TY - JOUR AU - Tait-Kamradt, A. AU - Davies, T. AU - Cronan, M. AU - Jacobs, M. R. AU - Appelbaum, P. C. AU - Sutcliffe, J. PY - 2000 DA - 2000// TI - Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage JO - Antimicrob Agents Chemother VL - 44 UR - https://doi.org/10.1128/AAC.44.8.2118-2125.2000 DO - 10.1128/AAC.44.8.2118-2125.2000 ID - Tait-Kamradt2000 ER - TY - JOUR AU - Rodriguez-Fonseca, C. AU - Amils, R. AU - Garrett, R. A. PY - 1995 DA - 1995// TI - Fine structure of the peptidyl transferase centre on 23 S-like rRNAs deduced from chemical probing of antibiotic-ribosome complexes JO - J Mol Biol VL - 247 UR - https://doi.org/10.1006/jmbi.1994.0135 DO - 10.1006/jmbi.1994.0135 ID - Rodriguez-Fonseca1995 ER - TY - JOUR AU - Porse, B. T. AU - Kirillov, S. V. AU - Awayez, M. J. AU - Garrett, R. A. PY - 1999 DA - 1999// TI - UV-induced modifications in the peptidyl transferase loop of 23S rRNA dependent on binding of the streptogramin B antibiotic, pristinamycin IA JO - Rna VL - 5 UR - https://doi.org/10.1017/S135583829998202X DO - 10.1017/S135583829998202X ID - Porse1999 ER - TY - JOUR AU - Porse, B. T. AU - Garrett, R. A. PY - 1999 DA - 1999// TI - Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their inhibitory mechanisms JO - J Mol Biol VL - 286 UR - https://doi.org/10.1006/jmbi.1998.2509 DO - 10.1006/jmbi.1998.2509 ID - Porse1999 ER - TY - JOUR AU - Pioletti, M. AU - Schlunzen, F. AU - Harms, J. AU - Zarivach, R. AU - Gluhmann, M. AU - Avila, H. AU - Bashan, A. AU - Bartels, H. AU - Auerbach, T. AU - Jacobi, C. AU - Hartsch, T. AU - Yonath, A. AU - Franceschi, F. PY - 2001 DA - 2001// TI - Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3 JO - Embo J VL - 20 UR - https://doi.org/10.1093/emboj/20.8.1829 DO - 10.1093/emboj/20.8.1829 ID - Pioletti2001 ER - TY - JOUR AU - Pihlajamaki, M. AU - Kataja, J. AU - Seppala, H. AU - Elliot, J. AU - Leinonen, M. AU - Huovinen, P. AU - Jalava, J. PY - 2002 DA - 2002// TI - Ribosomal mutations in Streptococcus pneumoniae clinical isolates JO - Antimicrob Agents Chemother VL - 46 UR - https://doi.org/10.1128/AAC.46.3.654-658.2002 DO - 10.1128/AAC.46.3.654-658.2002 ID - Pihlajamaki2002 ER - TY - JOUR AU - Pernodet, J. L. AU - Boccard, F. AU - Alegre, M. T. AU - Blondelet-Rouault, M. H. AU - Guerineau, M. PY - 1988 DA - 1988// TI - Resistance to macrolides, lincosamides and streptogramin type B antibiotics due to a mutation in an rRNA operon of Streptomyces ambofaciens JO - Embo J VL - 7 ID - Pernodet1988 ER - TY - JOUR AU - Parfait, R. AU - Di Giambattista, M. AU - Cocito, C. PY - 1981 DA - 1981// TI - Competition between erythromycin and virginiamycin for in vitro binding to the large ribosomal subunit JO - Biochim Biophys Acta VL - 654 UR - https://doi.org/10.1016/0005-2787(81)90177-5 DO - 10.1016/0005-2787(81)90177-5 ID - Parfait1981 ER - TY - JOUR AU - Kirillov, S. V. AU - Porse, B. T. AU - Garrett, R. A. PY - 1999 DA - 1999// TI - Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome JO - Rna VL - 5 UR - https://doi.org/10.1017/S1355838299990568 DO - 10.1017/S1355838299990568 ID - Kirillov1999 ER - TY - JOUR AU - Di Giambattista, M. AU - Chinali, G. AU - Cocito, C. PY - 1989 DA - 1989// TI - The molecular basis of the inhibitory activities of type A and type B synergimycins and related antibiotics on ribosomes JO - J Antimicrob Chemother VL - 24 UR - https://doi.org/10.1093/jac/24.4.485 DO - 10.1093/jac/24.4.485 ID - Di Giambattista1989 ER - TY - JOUR AU - Depardieu, F. AU - Courvalin, P. PY - 2001 DA - 2001// TI - Mutation in 23S rRNA responsible for resistance to 16-membered macrolides and streptogramins in Streptococcus pneumoniae JO - Antimicrob Agents Chemother VL - 45 UR - https://doi.org/10.1128/AAC.45.1.319-323.2001 DO - 10.1128/AAC.45.1.319-323.2001 ID - Depardieu2001 ER - TY - JOUR AU - Cocito, C. AU - Chinali, G. PY - 1985 DA - 1985// TI - Molecular mechanism of action of virginiamycin-like antibiotics (synergimycins) on protein synthesis in bacterial cell-free systems JO - J Antimicrob Chemother VL - 16 Suppl A UR - https://doi.org/10.1093/jac/16.suppl_A.35 DO - 10.1093/jac/16.suppl_A.35 ID - Cocito1985 ER - TY - JOUR AU - Chinali, G. AU - Di Giambattista, M. AU - Cocito, C. PY - 1987 DA - 1987// TI - Ribosome protection by tRNA derivatives against inactivation by virginiamycin M: evidence for two types of interaction of tRNA with the donor site of peptidyl transferase JO - Biochemistry VL - 26 UR - https://doi.org/10.1021/bi00380a016 DO - 10.1021/bi00380a016 ID - Chinali1987 ER - TY - JOUR AU - Pereyre, S. AU - Gonzalez, P. AU - De Barbeyrac, B. AU - Darnige, A. AU - Renaudin, H. AU - Charron, A. AU - Raherison, S. AU - Bebear, C. AU - Bebear, C. M. PY - 2002 DA - 2002// TI - Mutations in 23S rRNA account for intrinsic resistance to macrolides in Mycoplasma hominis and Mycoplasma fermentans and for acquired resistance to macrolides in M. hominis JO - Antimicrob Agents Chemother VL - 46 UR - https://doi.org/10.1128/AAC.46.10.3142-3150.2002 DO - 10.1128/AAC.46.10.3142-3150.2002 ID - Pereyre2002 ER - TY - JOUR AU - Kehoe, L. E. AU - Snidwongse, J. AU - Courvalin, P. AU - Rafferty, J. B. AU - Murray, I. A. PY - 2003 DA - 2003// TI - Structural basis of Synercid (quinupristin-dalfopristin) resistance in Gram-positive bacterial pathogens JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M303766200 DO - 10.1074/jbc.M303766200 ID - Kehoe2003 ER - TY - JOUR AU - Choi, K. M. AU - Atkins, J. F. AU - Gesteland, R. F. AU - Brimacombe, R. PY - 1998 DA - 1998// TI - Flexibility of the nascent polypeptide chain within the ribosome--contacts from the peptide N-terminus to a specific region of the 30S subunit JO - Eur J Biochem VL - 255 UR - https://doi.org/10.1046/j.1432-1327.1998.2550409.x DO - 10.1046/j.1432-1327.1998.2550409.x ID - Choi1998 ER - TY - JOUR AU - Harms, J. AU - Schluenzen, F. AU - Zarivach, R. AU - Bashan, A. AU - Gat, S. AU - Agmon, I. AU - Bartels, H. AU - Franceschi, F. AU - Yonath, A. PY - 2001 DA - 2001// TI - High resolution structure of the large ribosomal subunit from a mesophilic eubacterium JO - Cell VL - 107 UR - https://doi.org/10.1016/S0092-8674(01)00546-3 DO - 10.1016/S0092-8674(01)00546-3 ID - Harms2001 ER - TY - JOUR AU - Green, R. AU - Samaha, R. R. AU - Noller, H. F. PY - 1997 DA - 1997// TI - Mutations at nucleotides G2251 and U2585 of 23 S rRNA perturb the peptidyl transferase center of the ribosome JO - J Mol Biol VL - 266 UR - https://doi.org/10.1006/jmbi.1996.0780 DO - 10.1006/jmbi.1996.0780 ID - Green1997 ER - TY - JOUR AU - Wower, J. AU - Kirillov, S. V. AU - Wower, I. K. AU - Guven, S. AU - Hixson, S. S. AU - Zimmermann, R. A. PY - 2000 DA - 2000// TI - Transit of tRNA through the Escherichia coli ribosome. Cross-linking of the 3' end of tRNA to specific nucleotides of the 23 S ribosomal RNA at the A, P, and E sites JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M005031200 DO - 10.1074/jbc.M005031200 ID - Wower2000 ER - TY - JOUR AU - Bocchetta, M. AU - Xiong, L. AU - Mankin, A. S. PY - 1998 DA - 1998// TI - 23S rRNA positions essential for tRNA binding in ribosomal functional sites JO - Proc Natl Acad Sci U S A VL - 95 UR - https://doi.org/10.1073/pnas.95.7.3525 DO - 10.1073/pnas.95.7.3525 ID - Bocchetta1998 ER - TY - JOUR AU - Porse, B. T. AU - Thi-Ngoc, H. P. AU - Garrett, R. A. PY - 1996 DA - 1996// TI - The donor substrate site within the peptidyl transferase loop of 23 S rRNA and its putative interactions with the CCA-end of N-blocked aminoacyl-tRNA(Phe) JO - J Mol Biol VL - 264 UR - https://doi.org/10.1006/jmbi.1996.0655 DO - 10.1006/jmbi.1996.0655 ID - Porse1996 ER - TY - JOUR AU - Moazed, D. AU - Noller, H. F. PY - 1991 DA - 1991// TI - Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA JO - Proc Natl Acad Sci U S A VL - 88 UR - https://doi.org/10.1073/pnas.88.9.3725 DO - 10.1073/pnas.88.9.3725 ID - Moazed1991 ER - TY - JOUR AU - Bashan, A. AU - Agmon, I. AU - Zarivach, R. AU - Schluenzen, F. AU - Harms, J. AU - Berisio, R. AU - Bartels, H. AU - Franceschi, F. AU - Auerbach, T. AU - Hansen, H. A. AU - Kossoy, E. AU - Kessler, M. AU - Yonath, A. PY - 2003 DA - 2003// TI - Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression JO - Mol Cell VL - 11 UR - https://doi.org/10.1016/S1097-2765(03)00009-1 DO - 10.1016/S1097-2765(03)00009-1 ID - Bashan2003 ER - TY - JOUR AU - Hansen, J. L. AU - Schmeing, T. M. AU - Moore, P. B. AU - Steitz, T. A. PY - 2002 DA - 2002// TI - Structural insights into peptide bond formation JO - Proc Natl Acad Sci U S A VL - 99 UR - https://doi.org/10.1073/pnas.172404099 DO - 10.1073/pnas.172404099 ID - Hansen2002 ER - TY - JOUR AU - Agmon, I. AU - Auerbach, T. AU - Baram, D. AU - Bartels, H. AU - Bashan, A. AU - Berisio, R. AU - Fucini, P. AU - Hansen, H. A. AU - Harms, J. AU - Kessler, M. AU - Peretz, M. AU - Schluenzen, F. AU - Yonath, A. AU - Zarivach, R. PY - 2003 DA - 2003// TI - On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes JO - Eur J Biochem VL - 270 UR - https://doi.org/10.1046/j.1432-1033.2003.03634.x DO - 10.1046/j.1432-1033.2003.03634.x ID - Agmon2003 ER - TY - JOUR AU - Cannone, J. J. AU - Subramanian, S. AU - Schnare, M. N. AU - Collett, J. R. AU - D'Souza, L. M. AU - Du, Y. AU - Feng, B. AU - Lin, N. AU - Madabusi, L. V. AU - Muller, K. M. AU - Pande, N. AU - Shang, Z. AU - Yu, N. AU - Gutell, R. R. PY - 2002 DA - 2002// TI - The Comparative RNA Web (CRW) Site: an online database of comparative sequence and structure information for ribosomal, intron, and other RNAs: Correction JO - BMC Bioinformatics VL - 3 UR - https://doi.org/10.1186/1471-2105-3-15 DO - 10.1186/1471-2105-3-15 ID - Cannone2002 ER - TY - JOUR AU - Otwinowski, Z. AU - Minor, W. PY - 1997 DA - 1997// TI - Processing of X-ray diffraction data collected in oscillation mode JO - Method Enzymol VL - 276 UR - https://doi.org/10.1016/S0076-6879(97)76066-X DO - 10.1016/S0076-6879(97)76066-X ID - Otwinowski1997 ER - TY - JOUR AU - Bailey, S. PY - 1994 DA - 1994// TI - The Ccp4 Suite - Programs for Protein Crystallography JO - Acta Crystallogr D VL - 50 UR - https://doi.org/10.1107/S0907444993011898 DO - 10.1107/S0907444993011898 ID - Bailey1994 ER - TY - JOUR AU - Brunger, A. T. AU - Adams, P. D. AU - Clore, G. M. AU - DeLano, W. L. AU - Gros, P. AU - Grosse-Kunstleve, R. W. AU - Jiang, J. S. AU - Kuszewski, J. AU - Nilges, M. AU - Pannu, N. S. AU - Read, R. J. AU - Rice, L. M. AU - Simonson, T. AU - Warren, G. L. PY - 1998 DA - 1998// TI - Crystallography & NMR system: A new software suite for macromolecular structure determination JO - Acta Crystallogr D VL - 54 UR - https://doi.org/10.1107/S0907444998003254 DO - 10.1107/S0907444998003254 ID - Brunger1998 ER - TY - JOUR AU - Carson, M. PY - 1997 DA - 1997// TI - Ribbons JO - Method Enzymol VL - 277 UR - https://doi.org/10.1016/S0076-6879(97)77027-7 DO - 10.1016/S0076-6879(97)77027-7 ID - Carson1997 ER - TY - JOUR AU - Wallace, A. C. AU - Laskowski, R. A. AU - Thornton, J. M. PY - 1995 DA - 1995// TI - Ligplot - a Program to Generate Schematic Diagrams of Protein Ligand Interactions JO - Protein Eng VL - 8 UR - https://doi.org/10.1093/protein/8.2.127 DO - 10.1093/protein/8.2.127 ID - Wallace1995 ER - TY - JOUR AU - Berman, H. M. AU - Westbrook, J. AU - Feng, Z. AU - Gilliland, G. AU - Bhat, T. N. AU - Weissig, H. AU - Shindyalov, I. N. AU - Bourne, P. E. PY - 2000 DA - 2000// TI - The Protein Data Bank JO - Nucleic Acids Res VL - 28 UR - https://doi.org/10.1093/nar/28.1.235 DO - 10.1093/nar/28.1.235 ID - Berman2000 ER -