Skip to main content
Figure 1 | BMC Biology

Figure 1

From: Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

Figure 1

Interactions of streptogramins with 23S rRNA. (A) Chemical structure of quinupristin and dalfopristin. The hydrogen bonds towards 23S rRNA nucleotides are indicated. (B) Overview of the nucleotides involved in binding in comparison with those indicated by various biochemical and genetic experiments [5, 7, 12-30]. Both images contain numbering for E. coli (in green) and for D. radiodurans (in red). The sequence itself corresponds to 23S rRNA of D. radiodurans. All other images use numbering according to E. coli.

Back to article page

BMC Biology

ISSN: 1741-7007

Contact us