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Figure 3 | BMC Biology

Figure 3

From: Discs-large (DLG) is clustered by presynaptic innervation and regulates postsynaptic glutamate receptor subunit composition in Drosophila

Figure 3

Postsynaptic glutamate receptor current properties change in DLG mutants A: Single glutamate receptor channel current amplitudes from synaptic glutamate receptors are significantly larger in dlg mutants, compared to controls. Single channel amplitudes were measured from channels displaying delayed closing during the falling phase of spontaneous synaptic currents; examples of sEJCs showing single channel currents are shown in B. C: Glutamate-gated currents, evoked using pressure ejection of 1 mM glutamate onto embryonic NMJs, are smaller in dlg mutants, compared to controls. Sample glutamate-gated currents are shown in D. E: The frequency of spontaneous excitatory junction currents (sEJCs) is reduced in dlg mutants, compared to controls. F: sEJC amplitudes are not significantly different in dlg mutants, compared to controls.

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