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Table 6 Genes predicted to be under positive selection with the branch-site models.

From: Comparative analysis of protein coding sequences from human, mouse and the domesticated pig

Genbank Acc.

ω

P

Human gene annotation

Human lineage

   

NM_001785

3.8

0.27

Cytidine deaminase

NM_001867

5.3

0.20

Cytochrome c oxidase subunit VIIc

NM_004846

10.7

0.05

Eukaryotic translation initiation factor 4E-like 3

NM_006607

27.9

0.23

Pituitary tumor-transforming 2

NM_012198

4.8

0.32

Grancalcin, EF-hand calcium binding protein

NM_021167

6.9

0.13

Ocular development-associated gene (Interim)

NM_022978

22.0

0.28

Small EDRK-rich factor 1B (centromeric)

NM_080915

28.1

0.12

Deoxyguanosine kinase

XM_039644

49.5

0.02

Unclassified

XM_059906

8.2

0.07

Unclassified

XM_062742

2.0

0.84

Unclassified

XM_069411

6.8

0.38

Similar to RIKEN cDNA 1300003K24 (Interim)

XM_166695

6.9

0.31

Unclassified

XM_167131

3.8

0.28

Unclassified

XM_172026

16.9

0.38

Unclassified

Pig lineage

   

NM_000509

2.4

0.13

Fibrinogen, gamma polypeptide

NM_000520

10.3

0.06

Hexosaminidase A (alpha polypeptide)

NM_002979

2.0

0.15

Sterol carrier protein 2

NM_003142

3.1

0.14

Sjogren syndrome antigen B (autoantigen La) *

NM_016489

2.4

0.32

5'-nucleotidase, cytosolic III

Mouse lineage

   

NM_005731

8.6

0.074

Actin related protein 2/3 complex, subunit 2, 34 kDa

NM_013342

1.3

0.152

TCF3 (E2A) fusion partner (in childhood leukaemia)

NM_023935

3.0

0.171

Chromosome 20 open reading frame 116

XM_007076

2.5

0.248

Unclassified

  1. Genes shown here all have a significant LRT at the 0.001 level. (ω) the predicted dN/dS ratio in the foreground lineage. (p) the proportion of sites predicted to be under positive selection.