Comparative analysis of protein coding sequences from human, mouse and the domesticated pig

Table 8 Codon usage in the three mammalian species.

	Frequency				Frequency				Frequency				Frequency
Codon	H	M	P	Codon	H	M	P	Codon	H	M	P	Codon	H	M	P
TTT(F)	2.16	2.00	2.06	TCT(S)	1.43	1.44	1.38	TAT(Y)	1.61	1.40	1.48	TGT(C)	1.03	0.99	0.97
TTC	1.85	2.01	1.93	TCC	1.30	1.40	1.37	TAC	1.48	1.64	1.60	TGC	0.92	0.97	0.96
TTA(L)	0.98	0.81	0.89	TCA	1.12	1.01	1.04	*TAA()**	0	0	0	*TGA()**	0	0	0
TTG	1.50	1.42	1.46	TCG	0.33	0.39	0.40	*TAG()**	0	0	0	TGG(W)	1.24	1.23	1.23
CTT	1.53	1.40	1.44	CCT(P)	1.66	1.62	1.60	CAT(H)	1.17	1.05	1.07	CGT(R)	0.53	0.49	0.51
CTC	1.55	1.67	1.70	CCC	1.35	1.37	1.48	CAC	1.15	1.31	1.25	CGC	0.79	0.80	0.83
CTA	0.83	0.78	0.74	CCA	1.63	1.58	1.53	CAA(Q)	1.30	1.18	1.19	CGA	0.75	0.79	0.76
CTG	3.32	3.60	3.48	CCG	0.47	0.55	0.54	CAG	3.03	3.17	3.13	CGG	0.99	1.02	1.06
ATT(I)	2.16	1.90	2.01	ACT(T)	1.42	1.30	1.32	AAT(N)	2.05	1.73	1.88	AGT(S)	1.18	1.12	1.13
ATC	2.06	2.24	2.20	ACC	1.53	1.61	1.62	AAC	1.76	1.99	1.86	AGC	1.39	1.52	1.44
ATA	0.92	0.84	0.88	ACA	1.64	1.59	1.50	AAA(K)	3.35	2.95	3.23	AGA(R)	1.46	1.40	1.42
ATG(M)	2.22	2.20	2.22	ACG	0.47	0.56	0.58	AAG	3.74	3.98	3.65	AGG	1.04	1.14	1.08
GTT(V)	1.49	1.37	1.41	GCT(A)	2.21	2.22	2.11	GAT(D)	2.93	2.59	2.79	GGT(G)	1.32	1.23	1.26
GTC	1.33	1.50	1.43	GCC	2.35	2.43	2.54	GAC	2.35	2.70	2.51	GGC	1.95	2.08	0.06
GTA	0.99	0.84	0.88	GCA	1.89	1.77	1.81	GAA(E)	3.77	3.44	3.62	GGA	2.05	1.95	1.97
GTG	2.66	2.82	2.75	GCG	0.63	0.75	0.73	GAG	3.51	3.79	3.66	GGG	1.28	1.35	1.34

The frequencies are expressed as a percentage of the 240,048 codons in each of the three species. Human(H), Mouse(M), Pig(P). Stop codons are not allowed in the analyses (*).

ISSN: 1741-7007