Figure 4 From: Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm H 2 O 2 causes DAF-16a::GFP to translocate to the cytoplasm. (A) Examples of muIs71 daf-16(mu86) worms, focussing on neurons of the nerve ring (arrows). DAF-16 is nuclear (after control treatment) or cytoplasmic (after H2O2 treatment). (B) Quantification of the effect of H2O2on DAF-16a::GFP localisation in muIs71 daf-16(mu86) worms with wild type age-1 and age-1(hx546). n = number of worms imaged. Number of independent experiments in brackets.Back to article page