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Figure 4 | BMC Biology

Figure 4

From: Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm

Figure 4

H 2 O 2 causes DAF-16a::GFP to translocate to the cytoplasm. (A) Examples of muIs71 daf-16(mu86) worms, focussing on neurons of the nerve ring (arrows). DAF-16 is nuclear (after control treatment) or cytoplasmic (after H2O2 treatment). (B) Quantification of the effect of H2O2on DAF-16a::GFP localisation in muIs71 daf-16(mu86) worms with wild type age-1 and age-1(hx546). n = number of worms imaged. Number of independent experiments in brackets.

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