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Table 1 Calcium response, genotype and wound healing.

From: The roles of calcium signaling and ERK1/2 phosphorylation in a Pax6 +/-mouse model of epithelial wound-healing delay

 

High [Ca]i

Healing

 

Initiation

Propagation

0–2 h

2–6 h

Pax6 +/+

+++

+++

+++

+++

No Ca2+ o

-

+

-

-

No Ca2+ i

+++

-

-

-

No P2Y

+++

-

-

-

+ ATP

+++

+++

+++

+++

Pax6 +/-

+++

+

-

+++

Pax6 +/- + ATP

+++

+

-

+++

Pax6 +/- + EGF

+++

+++

+++

+++

  1. +++, normal wild-type control response; +, subnormal response; -, response not detectable.