Figure 3

Profile of RNA polymerase alignment showing high level of conservation at intein insertion sites. The plot was generated from an alignment of multiple eukaryotic RNA polymerase I, II and III sequences using the PLOTSIMILARITY program of the GCG package of sequence analysis programs [49]. Intein location positions are as follows: BdeRPB2-c 843; Ddi RPC2 853; PnoRPA2 1195; P. ramorum virus, Sargasso Sea isolate, E. huxleyi virus 163 1516; SasRPB2-b, CstRPB2-b 1664; CreRPB2-a 1696. Intron locations are indicated by a short vertical line at their insertion site and are as follows: D. discoideum 1–111, 2–184; P. nodorum 5–301, 17–1192; B. dendrobatidis 13–826, 21–1357; C. reinhardtii 3–222, 4–295, 6–335, 7–376, 8–439, 9–545, 10–657, 11–709, 12–797, 14–867, 15–998, 16–1093, 18–1217, 19–1287, 20–1346, 22–1401, 23–1511, 24–1587, 25–1688, 26–1817.