|
Locus
|
Length (bp)*
|
Population
|
Sample size (n)†
|
S‡
|
Gene diversity ± SD
|
Nucleotide diversity, % (θ ± SD)
|
Nucleotide diversity, % (π ± SD)
|
FST (P§)
|
|---|
|
SDHA
|
5270
|
AA
|
24
|
35
|
0.974 ± 0.010
|
0.141 ± 0.045
|
0.231 ± 0.118
|
0.093 (0.012)
|
| | |
EA
|
24
|
27
|
0.903 ± 0.030
|
0.107 ± 0.036
|
0.147 ± 0.077
| |
| | |
All
|
48
|
36
|
0.964 ± 0.009
|
0.126 ± 0.037
|
0.199 ± 0.101
| |
|
SDHB
|
1722
|
AA
|
24
|
3
|
0.231 ± 0.078
|
0.039 ± 0.024
|
0.016 ± 0.019
|
0.061 (0.113)
|
| | |
EA
|
24
|
0
|
0
|
0
|
0
| |
| | |
All
|
48
|
3
|
0.120 ± 0.045
|
0.034 ± 0.021
|
0.008 ± 0.013
| |
|
SDHC
|
1813
|
AA
|
24
|
8
|
0.680 ± 0.060
|
0.086 ± 0.040
|
0.103 ± 0.067
|
0.176 (~0)
|
| | |
EA
|
24
|
2
|
0.082 ± 0.053
|
0.012 ± 0.012
|
0.013 ± 0.017
| |
| | |
All
|
48
|
8
|
0.441 ± 0.061
|
0.075 ± 0.033
|
0.065 ± 0.046
| |
|
SDHD
|
2036
|
AA
|
24
|
5
|
0.609 ± 0.063
|
0.055 ± 0.028
|
0.077 ± 0.052
|
0.234 (~0)
|
| | |
EA
|
24
|
0
|
0
|
0
|
0
| |
| | |
All
|
48
|
5
|
0.361 ± 0.059
|
0.048 ± 0.024
|
0.044 ± 0.034
| |
- AA, African American samples; EA, European American samples; SD, standard deviation.
- *Includes coding and non-coding sequences.
- †Number of unrelated subjects.
- ‡Number of segregating sites.
- §p value for population genetic structure between AA and EA.
