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Table 2 Sequence diversity in succinate dehydrogenase subunit genes

From: Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA

Locus Length (bp)* Population Sample size (n)† S‡ Gene diversity ± SD Nucleotide diversity, % (θ ± SD) Nucleotide diversity, % (π ± SD) FST (P§)
SDHA 5270 AA 24 35 0.974 ± 0.010 0.141 ± 0.045 0.231 ± 0.118 0.093 (0.012)
   EA 24 27 0.903 ± 0.030 0.107 ± 0.036 0.147 ± 0.077  
   All 48 36 0.964 ± 0.009 0.126 ± 0.037 0.199 ± 0.101  
SDHB 1722 AA 24 3 0.231 ± 0.078 0.039 ± 0.024 0.016 ± 0.019 0.061 (0.113)
   EA 24 0 0 0 0  
   All 48 3 0.120 ± 0.045 0.034 ± 0.021 0.008 ± 0.013  
SDHC 1813 AA 24 8 0.680 ± 0.060 0.086 ± 0.040 0.103 ± 0.067 0.176 (~0)
   EA 24 2 0.082 ± 0.053 0.012 ± 0.012 0.013 ± 0.017  
   All 48 8 0.441 ± 0.061 0.075 ± 0.033 0.065 ± 0.046  
SDHD 2036 AA 24 5 0.609 ± 0.063 0.055 ± 0.028 0.077 ± 0.052 0.234 (~0)
   EA 24 0 0 0 0  
   All 48 5 0.361 ± 0.059 0.048 ± 0.024 0.044 ± 0.034  
  1. AA, African American samples; EA, European American samples; SD, standard deviation.
  2. *Includes coding and non-coding sequences.
  3. †Number of unrelated subjects.
  4. ‡Number of segregating sites.
  5. §p value for population genetic structure between AA and EA.
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