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Table 1 Specific scaling exponents of the regional cerebral glucose utilization rate CMRglc against brain volume

From: Global and regional brain metabolic scaling and its functional consequences

Brain structure Scaling exponent 95% confidence intervals Correlation R2 p-value Species (n)
Cerebral cortex -0.15 ± 0.03 -0.22 to -0.08 0.870 0.0022 7
   Visual -0.12 ± 0.03 -0.17 to -0.08 0.932 0.0018 6
   Prefrontal -0.17 ± 0.03 -0.23 to -0.10 0.953 0.0044 5
   Frontal -0.14 ± 0.02 -0.17 to -0.12 0.997 0.0015 4
   Sensorimotor -0.15 ± 0.02 -0.19 to -0.11 0.945 0.0002 7
   Parietal -0.15 ± 0.03 -0.20 to -0.11 0.954 0.0008 6
   Temporal -0.15 ± 0.05 -0.27 to -0.03 0.680 0.0224 7
   Cingulate -0.16 ± 0.03 -0.23 to -0.09 0.912 0.0030 6
   Occipital -0.20 ± 0.12 -0.53 to 0.12 0.563 0.1439 5
Thalamus -0.15 ± 0.03 -0.22 to -0.08 0.858 0.0027 7
Hypothalamus -0.10 ± 0.04 -0.20 to -0.01 0.692 0.0402 6
   Mammillary body -0.15 ± 0.07 -0.30 to -0.00 0.773 0.0495 5
Cerebellum -0.15 ± 0.04 -0.24 to -0.06 0.840 0.0102 6
Basal ganglia      
   Caudate -0.15 ± 0.03 -0.22 to -0.08 0.905 0.0035 6
   Substantia nigra -0.14 ± 0.02 -0.18 to -0.10 0.956 0.0007 6
   Globus pallidus -0.16 ± 0.04 -0.24 to -0.08 0.926 0.0088 5
Limbic system      
   Hippocampus -0.14 ± 0.03 -0.19 to -0.09 0.919 0.0007 7
   Amygdala -0.12 ± 0.03 -0.17 to -0.07 0.919 0.0025 6
   Septum -0.16 ± 0.03 -0.23 to -0.09 0.944 0.0057 5
Brain stem      
   Superior colliculus -0.06 ± 0.05 -0.19 to 0.06 0.448 0.2168 5
   Inferior colliculus 0.05 ± 0.09 -0.14 to 0.23 0.174 0.4843 5
White matter      
   Corpus callosum -0.23 ± 0.09 -0.40 to -0.06 0.947 0.0271 4
   Internal capsule -0.24 ± 0.12 -0.48 to 0.00 0.902 0.0504 4
  1. The t-test showed that population mean of the exponents in the second column was significantly greater than the exponent -0.25 (p = 9 × 10-9, degrees of freedom (df) = 21 if white matter included; p = 2 × 10-9, df = 19 if white matter excluded).