TY - JOUR AU - Hellsten, Uffe AU - Khokha, Mustafa K. AU - Grammer, Timothy C. AU - Harland, Richard M. AU - Richardson, Paul AU - Rokhsar, Daniel S. PY - 2007 DA - 2007/07/25 TI - Accelerated gene evolution and subfunctionalization in the pseudotetraploid frog Xenopus laevis JO - BMC Biology SP - 31 VL - 5 IS - 1 AB - Ancient whole genome duplications have been implicated in the vertebrate and teleost radiations, and in the emergence of diverse angiosperm lineages, but the evolutionary response to such a perturbation is still poorly understood. The African clawed frog Xenopus laevis experienced a relatively recent tetraploidization ~40 million years ago. Analysis of the considerable amount of EST sequence available for this species together with the genome sequence of the related diploid Xenopus tropicalis provides a unique opportunity to study the genomic response to whole genome duplication. SN - 1741-7007 UR - https://doi.org/10.1186/1741-7007-5-31 DO - 10.1186/1741-7007-5-31 ID - Hellsten2007 ER -