Identification of novel conserved peptide uORF homology groups in Arabidopsis and rice reveals ancient eukaryotic origin of select groups and preferential association with transcription factor-encoding genes

Table 4 Arabidopsis loci with conserved peptide uORFs identified from Arabidopsis-Arabidopsis comparison

Homology group	Locus	Gene name	mORF description	Gene ontology molecular function	Recent duplicate
20	At3g53670.1		Expressed transcript	Unknown	At2g37480^a
20	At2g37480.1		Expressed transcript	Unknown	At3g53670^a
21	At1g68550.1	AtERF#118 ^b	Group VI-L ERF/AP2 transcription factor	Transcription factor	At1g25470
21	At1g25470.1	AtERF#116 ^b	Group VI-L ERF/AP2 transcription factor	Transcription factor	At1g68550
22	At1g16860.1		Expressed transcript	Unknown	At1g78880
22	At1g78880.1		Expressed transcript	Unknown	At1g16860
23	At1g64630.1	ZIK10	MAP kinase, PPC Family 4.1.5	Transcription factor	Not found
23	At5g41990.1	WNK8/ZIK6	MAP kinase, PPC family 4.1.5	Protein kinase	Not found
24	At3g22970.1		Expressed transcript	Unknown	At4g14620
24	At4g14620.1		Expressed transcript	Unknown	At3g22970
25	At3g45240.1^c		Calcium response kinase, PPC family 4.2.7	ATP binding, protein kinase	At5g60550
25	At5g60550.1		Calcium response kinase, PPC family 4.2.7	ATP binding, protein kinase	At3g45240
26	At3g10910.1		Zinc finger, C3HC4-type (RING finger)	Protein binding, zinc ion binding	At5g05280
26	At5g05280.1		Zinc finger, C3HC4-type (RING finger)	Protein binding, zinc ion binding	At3g10910

ERF/AP2, Ethylene Response Factor/Apetela 2 transcription factor; PPC, PlantsP protein kinase classification.
^aBlanc and Wolfe (2004) report that At2g3790 and At3g53670 are retained recent duplicates, but the At2g3790 locus has since been replaced by At2g3780.
^bAs defined by Nakano, et al [97] and previously characterized as part of subfamily B-6 by Sakuma, et al [100].
^cuORF found upstream of annotated mORF-containing locus (within 2 kb).

ISSN: 1741-7007