Figure 1
From: The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules
TbHydin RNAi-induced cells grow slowly and do not locomote. (A) Representative growth curve shows growth defect starting 48 h after RNAi induction in TbHydin RNAi-induced cells (black squares) compared to non-induced controls (triangles). Cells were maintained in log phase by diluting the culture every 24 h. (B and C) Trajectories of individual cells over the course of a 40 s time-lapse. While non-induced control cells (B) are motile, cells locomotion is severely compromised in TbHydin RNA-induced cells (C).