Figure 3

Antisense intronic transcription may regulate the levels and the post-transcriptional processing of sense protein-coding mRNAs. (A-D) Expression levels of sense, antisense intronic transcripts ("intronic" panels) or specific exons of protein-coding messages ("exonic" panels) from GAS6 (A), DNAJC3 (B), KDELR2 (C) or ITGA6 (D) loci were measured in androgen-treated (black bars) or control cells (white bars). Full-length curator-confirmed mRNAs mapping to each loci are shown as black arrows; non-curator-confirmed mRNAs and ESTs are shown by gray arrows; androgen-regulated intronic unspliced transcripts are shown by hashed arrows. Relative fold change (Y axis) indicates the increase or decrease in transcript levels after androgen-treatment relative to their levels in untreated control cells. Error bars refer to standard deviations relative to mean fold-change values.