Table 3 The interactions shared by PPIs of structurally different Ribonucleases with inhibitors. Each pair of rows details the interacting pseudocenters of two PPI chains. Each three columns present the details of a specific PPI: (i) chain identifier and residue number; (ii) residue type; (iii) pseudocenter type, which can be donor (DON), acceptor (ACC), mixed donor/acceptor (DAC), hydrophobic aliphatic (ALI) or aromatic (PI). The last column presents the origin of the feature: backbone(b) or side-chain(s) if it is the same for all the matched pseudocenters.
From: Spatial chemical conservation of hot spot interactions in protein-protein complexes
1brs:Barstar(D)-Barnase(A) | 1ay7:Barstar(B)-RNase Sa(A) | 1a4y:RI(A)-Angiogenin(B) | Â | ||||||
|---|---|---|---|---|---|---|---|---|---|
Chain. R. Num | R. Type | Psc. Type | Chain R. Num | R. Type | Psc. Type | Chain R. Num | R. Type | Psc. Type | Type |
D.35 | Asp | PI:C | B.35 | Asp | PI:C | A.435 | Asp | PI:C | b |
A.103 | Tyr | PI: | A.86 | Tyr | PI | B.114 | His | PI | s |
D.35 | Asp | ACC | B.35 | Asp | ACC | A.435 | Asp | ACC | s |
A.59 | Arg | DON | A.40 | Arg | DON | B.40 | Lys | DON | Â |
D.39 | Asp | ACC | B.39 | Asp | ACC | A.438 | Trp | ACC | Â |
A.83 | Arg | DON | A.65 | Arg | DON | B.5 | Arg | DON | s |
D.39 | Asp | ACC | B.39 | Asp | ACC | A.438 | Trp | ACC | Â |
A.83 | Arg | DON | A.32 | Gln | DON | B.5 | Arg | DON | s |