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Table 1 Numbers of human genes, pseudogenes and gene families in each homeobox gene class. The human homeobox gene superclass contains a total of 235 probable functional genes and 65 probable pseudogenes. These are divided between 102 gene families, which are in turn divided between eleven gene classes.

From: Classification and nomenclature of all human homeobox genes

Class

Subclass

Number of gene families

Number of genes

Number of pseudogenes

ANTP

HOXL

14

52

0

 

NKL

23

48

19b

PRD

PAX

3

7a

0

 

PAXL

28

43

24c, d

LIM

 

6

12

0

POU

 

7

16

8e

HNF

 

2

3

0

SINE

 

3

6

0

TALE

 

6

20

10f

CUT

 

3

7

3g

PROS

 

1

2

0

ZF

 

5

14

1h

CERS

 

1

5i

0

Totals

 

102

235 a

65 b-h

  1. aIncludes PAX2, PAX5 and PAX8 that have a partial homeobox; excludes PAX1 and PAX9 that lack a homeobox.
  2. bIncludes NANOGP11 that lacks a homeobox.
  3. cExcludes intronless and repetitive DUX1 to DUX5 sequences.
  4. dIncludes TPRX1P1 and TPRX1P2 that lack a homeobox.
  5. eIncludes POU5F1P7 and POU5F1P8 that lack a homeobox.
  6. fIncludes IRX4P1, TGIF2P2, TGIF2P3 and TGIF2P4 that lack a homeobox.
  7. gIncludes CUX2P1, CUX2P2 and SATB1P1 that lack a homeobox.
  8. hIncludes ZEB2P1 that lacks a homeobox.
  9. iExcludes CERS1 that lacks a homeobox.