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Table 1 Numbers of human genes, pseudogenes and gene families in each homeobox gene class. The human homeobox gene superclass contains a total of 235 probable functional genes and 65 probable pseudogenes. These are divided between 102 gene families, which are in turn divided between eleven gene classes.

From: Classification and nomenclature of all human homeobox genes

Class Subclass Number of gene families Number of genes Number of pseudogenes
ANTP HOXL 14 52 0
  NKL 23 48 19b
PRD PAX 3 7a 0
  PAXL 28 43 24c, d
LIM   6 12 0
POU   7 16 8e
HNF   2 3 0
SINE   3 6 0
TALE   6 20 10f
CUT   3 7 3g
PROS   1 2 0
ZF   5 14 1h
CERS   1 5i 0
Totals   102 235 a 65 b-h
  1. aIncludes PAX2, PAX5 and PAX8 that have a partial homeobox; excludes PAX1 and PAX9 that lack a homeobox.
  2. bIncludes NANOGP11 that lacks a homeobox.
  3. cExcludes intronless and repetitive DUX1 to DUX5 sequences.
  4. dIncludes TPRX1P1 and TPRX1P2 that lack a homeobox.
  5. eIncludes POU5F1P7 and POU5F1P8 that lack a homeobox.
  6. fIncludes IRX4P1, TGIF2P2, TGIF2P3 and TGIF2P4 that lack a homeobox.
  7. gIncludes CUX2P1, CUX2P2 and SATB1P1 that lack a homeobox.
  8. hIncludes ZEB2P1 that lacks a homeobox.
  9. iExcludes CERS1 that lacks a homeobox.