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Table 4 Human LIM, POU, HNF, SINE, TALE, CUT, PROS, ZF AND CERS class homeobox genes and pseudogenes

From: Classification and nomenclature of all human homeobox genes

Human LIM-class homeobox genes

Family

Gene symbol

Gene name

Location

Entrez gene ID

Previous symbols

Isl

ISL1

ISL LIM homeobox 1

5q11.2

3670

 
 

ISL2

ISL LIM homeobox 2

15q24.3

64843

 

Lhx1/5

LHX1

LIM homeobox 1

17q12

3975

LIM1

 

LHX5

LIM homeobox 5

12q24.13

64211

 

Lhx2/9

LHX2

LIM homeobox 2

9q33.3

9355

LH2

 

LHX9

LIM homeobox 9

1q31.3

56956

 

Lhx3/4

LHX3

LIM homeobox 3

9q34.3

8022

M2-LHX3

 

LHX4

LIM homeobox 4

1q25.3

89884

GSH4

Lhx6/8

LHX6

LIM homeobox 6

9q33.2

26468

LHX6.1

 

LHX8

LIM homeobox 8

1p31.1

431707

LHX7

Lmx

LMX1A

LMX LIM homeobox 1A

1q24.1

4009

LMX1, LMX1.1

 

LMX1B

LMX LIM homeobox 1B

9q33.3

4010

LMX2, LMX1.2

Human POU-class homeobox genes and pseudogenes

Hdx

HDX

highly divergent homeobox

Xq21.1

139324

CXorf43

Pou1

POU1F1

POU class 1 homeobox 1

3p11.2

5449

PIT1, GHF1

Pou2

POU2F1

POU class 2 homeobox 1

1q24.2

5451

OCT1, OTF1

 

POU2F2

POU class 2 homeobox 2

19q13.2

5452

OCT2, OTF2

 

POU2F3

POU class 2 homeobox 3

11q23.3

25833

OCT11, PLA1, EPOC1, SKN1A

Pou3

POU3F1

POU class 3 homeobox 1

1p34.3

5453

OCT6, OTF6, SCIP

 

POU3F2

POU class 3 homeobox 2

6q16.2

5454

OCT7, OTF7, BRN2, POUF3

 

POU3F3

POU class 3 homeobox 3

2q12.1

5455

OTF8, BRN1

 

POU3F4

POU class 3 homeobox 4

Xq21.1

5456

OTF9, BRN4

Pou4

POU4F1

POU class 4 homeobox 1

13q31.1

5457

BRN3A, RDC1, Oct-T1

 

POU4F2

POU class 4 homeobox 2

4q31.22

5458

BRN3B, BRN3.2

 

POU4F3

POU class 4 homeobox 3

5q32

5459

BRN3C

Pou5

POU5F1

POU class 5 homeobox 1

6p21.33

5460

OCT3, OTF3, OCT4, OTF4

 

POU5F1P1

POU class 5 homeobox 1 pseudogene 1

8q24.21

5462

OTF3C, OTF3P1, POU5FLC8

 

POU5F1P2

POU class 5 homeobox 1 pseudogene 2

8q22.3

100009665

 
 

POU5F1P3

POU class 5 homeobox 1 pseudogene 3

12p13.31

642559

OTF3L, POU5F1L, POU5FLC12

 

POU5F1P4

POU class 5 homeobox 1 pseudogene 4

1q22

645682

POU5FLC1

 

POU5F1P5

POU class 5 homeobox 1 pseudogene 5

10q21.3

100009667

 
 

POU5F1P6

POU class 5 homeobox 1 pseudogene 6

3q21.3

100009668

 
 

POU5F1P7

POU class 5 homeobox 1 pseudogene 7

3q12.1

100009669

 
 

POU5F1P8

POU class 5 homeobox 1 pseudogene 8

17q25.3

100009670

 
 

POU5F2

POU class 5 homeobox 2

5q15

134187

SPRM1

Pou6

POU6F1

POU class 6 homeobox 1

12q13.13

5463

BRN5, MPOU, TCFB1

 

POU6F2

POU class 6 homeobox 2

7p14.1

11281

WT5, WTSL, RPF1

Human HNF-class homeobox genes

Hmbox

HMBOX1

homeobox containing 1

8p12

79618

HNF1LA, PBHNF

Hnf1

HNF1A

HNF1 homeobox A

12q24.31

6927

TCF1, HNF1, LFB1

 

HNF1B

HNF1 homeobox B

17q12

6928

TCF2, LFB3, VHNF1

Human SINE-class homeobox genes

Six1/2

SIX1

SIX homeobox 1

14q23.1

6495

 
 

SIX2

SIX homeobox 2

2p21

10736

 

Six3/6

SIX3

SIX homeobox 3

2p21

6496

 
 

SIX6

SIX homeobox 6

14q23.1

4990

OPTX2, Six9

Six4/5

SIX4

SIX homeobox 4

14q23.1

51804

AREC3

 

SIX5

SIX homeobox 5

19q13.32

147912

DMAHP

Human TALE-class homeobox genes and pseudogenes

Irx

IRX1

iroquois homeobox 1

5p15.33

 

IRX-5

 

IRX1P1

iroquois homeobox 1 pseudogene 1

13q12.12

79192

IRXA1

 

IRX2

iroquois homeobox 2

5p15.33

646390

 
 

IRX3

iroquois homeobox 3

16q12.2

153572

IRX-1

 

IRX4

iroquois homeobox 4

5p15.33

50805

 
 

IRX4P1

iroquois homeobox 4 pseudogene 1

18p11.22

100009671

 
 

IRX5

iroquois homeobox 5

16q12.2

79190

IRX2A

 

IRX6

iroquois homeobox 6

16q12.2

 

IRX-3, IRX7

Meis

MEIS1

Meis homeobox 1

2p14

4211

 
 

MEIS2

Meis homeobox 2

15q14

4212

MRG1

 

MEIS3

Meis homeobox 3

19q13.32

56917

MRG2

 

MEIS3P1

Meis homeobox 3 pseudogene 1

17p12

4213

MRG2, MEIS3, MEIS4

 

MEIS3P2

Meis homeobox 3 pseudogene 2

17p11.2

257468

 

Mkx

MKX

mohawk homeobox

10p12.1

283078

IRXL1, IFRX, C10orf48

Pbx

PBX1

pre-B-cell leukemia homeobox 1

1q23.3

5087

 
 

PBX2

pre-B-cell leukemia homeobox 2

6p21.32

5089

G17, HOX12, PBX2MHC

 

PBX2P1

pre-B-cell leukemia homeobox 2 pseudogene 1

3q24

5088

PBXP1, PBX2

 

PBX3

pre-B-cell leukemia homeobox 3

9q33.3

5090

 
 

PBX4

pre-B-cell leukemia homeobox 4

19p13.11

80714

 

Pknox

PKNOX1

PBX/knotted homeobox 1

21q22.3

5316

PREP1, PKNOX1C

 

PKNOX2

PBX/knotted homeobox 2

11q24.2

63876

PREP2

Tgif

TGIF1

TGFB-induced factor homeobox 1

18p11.31

7050

TGIF, HPE4

 

TGIF1P1

TGFB-induced factor homeobox1 pseudogene 1

19q13.32

126052

 
 

TGIF2

TGFB-induced factor homeobox 2

20q11.23

60436

 
 

TGIF2P1

TGFB-induced factor homeobox 2 pseudogene 1

1q44

126826

 
 

TGIF2P2

TGFB-induced factor homeobox 2 pseudogene 2

15q21.1

100009674

 
 

TGIF2P3

TGFB-induced factor homeobox 2 pseudogene 3

15q21.1

100009672

 
 

TGIF2P4

TGFB-induced factor homeobox 2 pseudogene 4

14q24.2

100009673

 
 

TGIF2LX

TGFB-induced factor homeobox 2-like, X-linked

Xq21.31

90316

TGIFLX (retrogene)

 

TGIF2LY

TGFB-induced factor homeobox 2-like, Y-linked

Yp11.2

90655

TGIFLY (retrogene)

Human CUT-class homeobox genes and pseudogenes

Onecut

ONECUT1

one cut homeobox 1

15q21.3

3175

HNF6, HNF6A

 

ONECUT2

one cut homeobox 2

18q21.31

9480

OC2

 

ONECUT3

one cut homeobox 3

19p13.3

390874

 

Cux

CUX1

cut-like homeobox 1

7q22.1

1523

CUTL1, CUX, CDP, COY1

 

CUX2

cut-like homeobox 2

12q24.12

23316

CUTL2

 

CUX2P1

cut-like homeobox 2 pseudogene 1

10p14

-

 
 

CUX2P2

cut-like homeobox 2 pseudogene 2

4q32.1

-

 

Satb

SATB1

SATB homeobox 1

3p24.3

6304

 
 

SATB2

SATB homeobox 2

2q33.1

23314

 

Human PROS-class homeobox genes

Prox

PROX1

prospero homeobox 1

1q41

5629

 
 

PROX2

prospero homeobox 2

14q24.3

283571

 

Human ZF-class homeobox genes and pseudogenes

Adnp

ADNP

activity-dependent neuroprotector homeobox

20q13.13

23394

ADNP1

 

ADNP2

ADNP homeobox 2

18q23

22850

ZNF508

Tshz

TSHZ1

teashirt zinc finger homeobox 1

18q22.3

10194

TSH1

 

TSHZ2

teashirt zinc finger homeobox 2

20q13.2

128553

TSH2, ZNF218, ZABC2, OVC10-2

 

TSHZ3

teashirt zinc finger homeobox 3

19q12

57616

TSH3, ZNF537

Zeb

ZEB1

zinc finger E-box binding homeobox 1

10p11.22

6935

ZFHX1A, deltaEF1, TCF8, ZEB

 

ZEB2

zinc finger E-box binding homeobox 2

2q22.3

9839

ZFHX1B, SIP1, SMADIP1

 

ZEB2P1

zinc finger E-box binding homeobox 2 pseudogene 1

4p15.32

100033412

 

Zfhx

ZFHX2

zinc finger homeobox 2

14q11.2

85446

 
 

ZFHX3

zinc finger homeobox 3

16q22.3

463

ATBT, ATBF1

 

ZFHX4

zinc finger homeobox 4

8q21.11

79776

ZFH4

Zhx/

ZHX1

zinc fingers and homeoboxes 1

8q24.13

11244

 

Homez

ZHX2

zinc fingers and homeoboxes 2

8q24.13

22882

 
 

ZHX3

zinc fingers and homeoboxes 3

20q12

23051

TIX1

 

HOMEZ

homeobox and leucine zipper encoding

14q11.2

57594

 

Human CERS-class homeobox genes

Cers

CERS2

ceramide synthase 2

1p36.13-q24.1

29956

LASS2, TRH3, TMSG1

 

CERS3

ceramide synthase 3

15q26.3

204219

LASS3

 

CERS4

ceramide synthase 4

19p13.3

79603

LASS4, TRH1

 

CERS5

ceramide synthase 5

12q13.12

91012

LASS5, TRH4

 

CERS6

ceramide synthase 6

2q31

253782

LASS6

  1. Human homeobox genes and pseudogenes, excepting the ANTP and PRD classes, including full names, chromosomal locations, Entrez Gene IDs and previous symbols. The HOMEZ gene is in the ZF class but encodes a protein with leucine zippers instead of zinc fingers.