Treatment with DHA or EPA increases the PrP
Sc content of ScGT1 cells. (A) The amounts of PrPSc in ScGT1 cells treated for 7 days with 1 μM PUFA as shown (■) or with control medium (□). Values shown are the mean average amounts of PrPSc (ng/ml) ± SD, n = 15. # = PrPSc content significantly higher than that of control cells. (B) Immunoblots showing the amounts of β-actin and PrPSc in extracts from ScGT1 cells treated with control medium or 1 μM DHA or EPA as shown.