DHA and EPA increases the amounts of activated cPLA
in ScGT1 cells. (A) The amounts of activated (phosphorylated) cPLA2 in untreated ScGT1 cells (□) or ScGT1 cells treated with 1 μM PUFA as shown (■). Values shown are the mean average amounts of activated cPLA2 (units) ± SD, n = 12. # = amounts of activated cPLA2 significantly higher than that of untreated cells. (B) The amounts of activated cPLA2 (units) in ScGT1 cells treated for 24 hours with different concentrations of DHA or EPA were plotted against the amounts of PrPSc (ng/ml) in ScGT1 cells treated for 7 days with the same concentrations of DHA (●) or EPA (○).