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Figure 2 | BMC Biology

Figure 2

From: Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2activation

Figure 2

PrP Sc causes a dose-dependent increase in the free cholesterol concentration of cortical neurons. The amounts of free cholesterol expressed as ng cholesterol/mg protein in cortical neurons treated for 48 hours with varying concentrations of PrPC (■) or PrPSc (□). Amounts of free cholesterol significantly greater than those of untreated neurons (P < 0.05) are indicated with *.

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