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Table 1 Prion infection increased the amounts of free cholesterol in neuronal cell lines. The amounts of total cholesterol, free cholesterol and esterified cholesterol (ng cholesterol/mg protein) in extracts from prion infected neuronal cells (ScN2a or ScGT1 cells) compared with their non-infected counterparts (N2a or GT1 cells). Values shown are the mean ± SD from 11 samples.

From: Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2activation

  Cholesterol (ng/mg protein)
    Esterified
  Total (mean ± SD) Free (mean ± SD) Mean ± SD Percentage
N2a 472 ± 47 384 ± 37 87 ± 19 18 ± 4
ScN2a 525 ± 34 473 ± 41 52 ± 14 10 ± 3
GT1 453 ± 72 368 ± 59 85 ± 28 19 ± 5
ScGT1 542 ± 44 500 ± 54 42 ± 14 8 ± 3