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Table 1 Significant gene ontology terms for changed genes

From: Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration

upregulated downregulated
NR5 and NR14 (N = 111) NR5 and NR14 (N = 104)
extracellular region (N = 14; 9.05E-07) muscle contraction (N = 13; 1.81E-10)
collagen catabolism (N = 5; 4.35E-06) cytoplasm (N = 51; 8.41E-07)
  collagen (N = 6; 4.05E-05)
  ion transport (N = 12; 9.44E-06)
NR5 only (N = 110) NR5 only (N = 49)
extracellular region (N = 15; 1.23E-05) extrinsic to membrane (N = 3; 6.10E-03)
response to stimulus (N = 17; 1.00E-02)  
signal transduction (N = 21; 2.89E-03)  
Ion transport (N = 9; 2.57E-03)  
NR14 only (N = 53) NR14 only (N = 93)
DNA metabolic process (N = 8; 4.41E-04) muscle contraction (N = 18; 5.43E-19)
  calcium ion binding (N = 11; 4.98E-04)
DL5 and DL14 (N = 170) DL5 and DL14 (N = 109)
extracellular region (N = 23; 6.64E-10) muscle contraction (N = 15; 6.62E-13)
lysosome (N = 11; 3.04E-08) cytoplasm (N = 53; 1.46E-06)
ion transport (N = 13; 1.42E-05) mitochondrial membrane (N = 12; 3.49E-04)
hydrolase activity (N = 26; 3.60E-05)  
response to stress (N = 21; 1.02E-03)  
signal transduction (N = 22; 5.40E-03)  
collagen catabolism (N = 5; 5.09E-05)  
DL5 only (N = 68) DL5 only (N = 58)
extracellular region (N = 9; 3.68E-04) extrinsic to membrane (N = 3; 4.64E-03)
response to stimulus (N = 12; 3.70E-03)  
DL14 only (N = 69) DL14 only (N = 111)
extracellular region (N = 7; 4.10E-03) muscle contraction (N = 9; 4.26E-05)
immune response (N = 5; 7.80E-03) mitochondrion (N = 27; 6.71E-07)
  cytoplasmic (N = 43; 2.58E-03)
  M phase (N = 9; 1.40E-03)
  glucose metabolic process (N = 6; 2.97E-03)
  1. Significant genes were identified by microarray analysis. Gene ontology terms are represented that were sampled more often than expected in NR5, NR14, DL5, and DL14 limbs. P-value is calculated by DAVID [45].