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Figure 7 | BMC Biology

Figure 7

From: Specific retention of the protostome-specific PsGEF may parallel with the evolution of mushroom bodies in insect and lophotrochozoan brains

Figure 7

Genetic interaction of DmPsGEF with Rho family members. The morphology of the alpha/beta lobes of mushroom bodies in wild-type (A), rac1 J11 /+ (B), and dmPsGEF Δ21hemizygous males (C) as well as under rho1 E3.10 (D), rac2 Δ (E), mtl Δ (F), rac1 J11 (H), and pak 6 (I) heterozygous background is shown. To determine the interactions with Cdc42 (G), dmPsGEF Δ21homozygous females with cdc42 4 heterozygous background were analyzed. The alpha and beta lobes are indicated by arrows in (A). The reduction of Rac1 gene dosage dramatically influences the phenotypes; a pair of alpha/beta lobes is missing in 90% of the examined animals (H).

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