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Table 10 Evidence that there are fewer alternatively spliced genes in nonsense-mediated mRNA decay under-represented functional classes in humans.

From: Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay

  Alla Non-NMDb
Biological process terms Non-AS AS AS Proportion P value Non-AS AS AS proportion P value
Developmental processes 286 1,304 0.82 1.27E-06 283 1271 0.82 1.43E-06
Cell surface receptor mediated signal transduction 224 834 0.79 3.40E-12 221 811 0.79 5.19E-12
Sensory perception 44 170 0.79 0.00699 44 165 0.79 0.00543
Signal transduction 416 2,029 0.83 2.44E-06 409 1960 0.83 2.31E-06
Chemosensory perception 5 5 0.50 0.00726 5 5 0.50 0.00767
Total genes 2,026 12,466 0.86   1987 12,047 0.86  
  1. Notes. NMD = nonsense-mediated mRNA decay. a all the genes with alternative splicing information were used. b only the genes that are not NMD candidates were used.