Skip to main content

Table 9 Biological process analysis of nonsense-mediated mRNA decay candidates.

From: Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay

 

Human

Mouse

Biological process terms

All genes

NMD genes

P value

All genes

NMD genes

P value

Biological process unclassified

6,172

327O

1.45 × 10-11

6080

244O

1.28 × 10-11

Developmental processes

1,908

43U

1.68 × 10-3

1867

32U

5.70 × 10-2

Cell-surface receptor-mediated signal transduction

1,513

30U

3.56 × 10-3

-

-

-

Sensory perception

465

5U

1.08 × 10-2

971

13U

7.10 × 10-2

Signal transduction

3,127

87U

1.44 × 10-2

3491

66U

8.75 × 10-3

Chemosensory perception

203

0

6.03 × 10-2

545

2U

5.14 × 10-3

Olfaction

-

-

-

539

2U

8.14 × 10-3

Total number of genes

18,172

693

 

17939

491

 
  1. Notes. NMD = nonsense-mediated mRNA decay. The biological processes with Bonferroni-corrected P values < 0.1 are listed; the complete result is presented in Additional file 3. O: biological process was over-represented in NMD candidates; U: biological process was under-represented in NMD candidates; symbol '-' indicates that the biological process exhibited a P value > 0.1 in this species, but not in the other species.