Analysis of selected readouts of cognitive performance in high-performer mice. (A) Number of acquisition days required for reaching performance criteria at each stimulus duration phase shows no group differences but a sharp increase in the transition from 4 sec to 2 sec. (B) The EPO-treated group showed faster task adaptation: The proportion of omissions in the first of six 10-trial blocks collapsed across the first 10 days of the 2-sec phase was significantly lower. Post hoc test. (C) The EPO-treated group showed higher stability of performance: the proportion of mice that relapsed from already reached performance criteria in the 2-sec stimulus duration phase was smaller. Chi2 test. (D) EPO improves performance stability even in the 1-sec phase: Proportion of total omissions over 4 days after reaching performance criteria was significantly lower in the EPO group. Mann-Whitney test. N = 7–28; data presented as mean ± S.E.M.