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Table 1 The effect of G proteins on the doubling time of cells

From: A Dictyostelium chalone uses G proteins to regulate proliferation

  Doubling time, hours
Cell type Low density High density
Wild-type 13.0 ± 0.6 35.4 ± 4.3
aprA - 9.7 ± 0.1** 20.7 ± 0.4*
cfaD - 10.9 ± 0.4* 17.7 ± 0.1**
gα2 - 13.9 ± 0.1 34.9 ± 3.3
gα5 - 12.2 ± 0.5 34.6 ± 1.3
gα7 - 12.2 ± 0.9 28.6 ± 5.4
gα8 - 10.9 ± 0.3* 13.4 ± 0.2**
gα9 - 10.1 ± 0.3** 18.3 ± 1.5**
gβ - 11.1 ± 0.4* 24.1 ± 3.0
  1. Doubling times were calculated using the data from Figure 2. Low density doubling times were calculated for cells in the range of 2 × 105 to 5 × 106 cells/ml. High density doubling times were calculated for cells in the range of 5 × 106 to 2 × 107 cells/ml. All values are means ± SEM's from three or more independent assays. A * indicates a statistically significant difference with p < 0.05; ** indicates p < 0.01, comparing the value to the wild type value (1-way ANOVA, Dunnett's test).
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BMC Biology

ISSN: 1741-7007

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