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Table 1 Summary of gene expression changes in cell lines treated with and without DMSO and/or RA.

From: Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by bone morphogenetic protein 4 but not dominant negative β-catenin

  

Cardiac

Skeletal Markers

 

Cell line

Conditions

GATA-4

Pax3

Gli2

Meox1

MRFs

Figure

P19

-

-

-

-

-

-

Fig. 7 & Data not shown

P19

+DMSO

+

+

+

+

+

Figs. 1 & 4

P19

+DMSO&RA

-

+++

+

+++

+++

Figs. 1 & 4

P19 [β-cat/EnR]

+DMSO

N.D.

-

-

-

-

Figs. 3 & 4

P19 [β-cat/EnR]

+DMSO&RA

N.D.

+++

+++

-

-

Figs. 3 & 4

P19 [BMP]

-

-

-

-

-

-

Data not shown

P19 [BMP]

+DMSO

+

-

N.D.

-

-

Fig. 6, 7 & 8

P19 [BMP]

+DMSO&RA

+

+++

N.D.

N.D.

+++

Fig. 8

Mouse ES

-

+

-

N.D.

+/-

-

Fig. 2

Mouse ES

+RA

+/-

+++

N.D.

+++

+++

Fig. 2

  1. P19 cell lines indicated on the right were aggregated under the conditions described and the induction of muscle marker gene expression was monitored.
  2. (+++ = high expression; + = normal expression; +/- = partial expression, - = not expressed; N.D. = not determined)