Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces

Table 4 GO analysis of differentially expressed genes of animals housed in different environments.

		IR vs OUT						IN vs OUT
GO Category	GO Term	Day 5		Day 28		Day 56		Day 5		Day 28		Day 56
		Genes*	P -value	Genes*	P -value	Genes*	P -value	Genes*	P -value	Genes*	P -value	Genes*	P -value
GO:0019882	Antigen processing and presentation	62	2.4E-33	28	8.0E-06	26	5.1E-05	25	6.0E-10	26	1.8E-07	26	8.8E-06
GO:0002376	Immune system process	65	3.5E-21	42	4.3E-07	33	0.001	27	1.6E-06	30	5.4E-05	35	2.7E-05
GO:0002474	Antigen processing and presentation of peptide antigen via MHC class I	15	1.6E-08	16	8.6E-10	15	7.8E-09	14	3.0E-11	15	1.5E-10	15	2.2E-09
GO:0048002	Antigen processing and presentation of peptide antigen	15	1.6E-08	16	8.6E-10	15	7.8E-09	14	3.0E-11	15	1.5E-10	15	2.2E-09
GO:0006955	Immune response	54	1.8E-16	31	4.7E-04			16	0.021			24	0.015
GO:0002504	Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	36	1.5E-17
GO:0050896	Response to stimulus	57	3.5E-07	41	0.018
GO:0006412	Translation									13	0.002
GO:0006807	Nitrogen compound metabolic process			9	0.007	8	0.021
GO:0030163	Protein catabolic process			5	0.008

Differentially expressed transcripts (P < 0.05) are shown assigned to the GO-category 'Biological Process'. The top ten GO-categories are shown. The number of transcripts for each function is shown, with the corresponding P-value.
*Genes involved in the specific GO-category

ISSN: 1741-7007