Figure 2

Functional and cellular categorization of proteins. Pie charts showing categories of 309 proteins according to (a) biological process, (b) molecular function, and (c) cellular location. Only the categories with at least five proteins have been included in the molecular function pie chart. Since a large number of categories were obtained from the Human Protein Reference Database (HPRD) for cellular localizations, they were classified into five major categories: cytoplasm (actin cytoskeleton, cytosol, and clathrin-coated vesicle), nucleus (centrosome, chromosome, and nucleolus), other intracellular organelles (ribosome, sarcoplasmic reticulum, sarcoplasm, mitochondrial matrix, mitochondrial membrane, mitochondrion, endoplasmic reticulum, golgi apparatus, lysosome and peroxisome), plasma membrane (integral to membrane) and extracellular (cell junction, extracellular matrix).