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Table 2 Highly regulated proteins

From: Proteomic analysis of blastema formation in regenerating axolotl limbs

Biological process Protein 1 day 4 days 7 days
Signaling associated CCDC88C 1.52 2.03 2.37
  GPR109B 2.38 1.61 2.65
  INVS -1.71 1.32 2.57
  IRS4 2.06 2.09 2.56
  ISYNA1 2.20 1.64 2.59
  ITSN2 2.86 1.96 2.32
  NET1 2.06 1.61 2.76
  NOS1 4.93* 1.91 1.16
  OR2AT4 1.67 138 2.01
  WNT8A 1.74 1.65 2.43
Ca2+ binding and translocation ATP11A 1.21 196 2.72
  HAK -1.43 -1.06 2.37
  PVALB -1.16 -1.35 -2.56
  SLC25A24 -1.71 1.32 2.57
Transcription and translation CWC15 -1.26 -1.74 -3.33*
  DDX46 1.18 -1.23 -2.22
  JMJD1B -1.05 -1.67 -6.82
  MNT 1.11 -1.26 -2.39
  NR2C2 2.32 2.06 2.05
  RPL7L1 2.47 1.54 1.17
  RPS20 1.63 1.80 3.61*
  ZNF777 -2.58 -2.23 -1.43
Cytoskeleton FHDC1 -1.22 -1.45 -2.06
  MYL3 -1.49 -1.62 -2.06
  MYL5 -1.45 -1.69 -2.04
  MYO1e 2.44 -1.05 NC
  MYO9A 2.21 NC NC
  NAV1 1.42 1.45 2.11
  PMFBP1 2.86 1.96 2.32
  SORBS1 -1.22 -1.57 -2.20
  ST3GAL5 2.07 1.87 1.96
  SYNE2 -1.68 1.20 2.67
  TM7 -1.17 -1.45 -2.10
  TNNT3A -1.17 -1.71 -2.01
Extracellular matrix COL13A1 1.41 1.49 2.66
  FGB 3.39* 1.63 1.14
  FGG 4.64* 2.17 1.14
  TINAG -1.68 -2.01 -2.77
Metabolism DAGLB 3.88* 1.26 1.49
  DHRS4 4.45* 3.93* 4.21*
Cell protection CYP2F1 -1.24 -1.55 -2.42
Degradation TMPRSS9 -1.07 -1.70 -6.95*
Cell cycle EVI5 4.00* 3.29* 3.85*
  1. Priority 1 and 2 proteins upregulated or downregulated by a value of 2.00 or more on one or more days post amputation (dpa). Asterisks indicate exceptionally high values (over 3.00) on one or more dpa.
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