Skip to main content

Table 2 Highly regulated proteins

From: Proteomic analysis of blastema formation in regenerating axolotl limbs

Biological process

Protein

1 day

4 days

7 days

Signaling associated

CCDC88C

1.52

2.03

2.37

 

GPR109B

2.38

1.61

2.65

 

INVS

-1.71

1.32

2.57

 

IRS4

2.06

2.09

2.56

 

ISYNA1

2.20

1.64

2.59

 

ITSN2

2.86

1.96

2.32

 

NET1

2.06

1.61

2.76

 

NOS1

4.93*

1.91

1.16

 

OR2AT4

1.67

138

2.01

 

WNT8A

1.74

1.65

2.43

Ca2+ binding and translocation

ATP11A

1.21

196

2.72

 

HAK

-1.43

-1.06

2.37

 

PVALB

-1.16

-1.35

-2.56

 

SLC25A24

-1.71

1.32

2.57

Transcription and translation

CWC15

-1.26

-1.74

-3.33*

 

DDX46

1.18

-1.23

-2.22

 

JMJD1B

-1.05

-1.67

-6.82

 

MNT

1.11

-1.26

-2.39

 

NR2C2

2.32

2.06

2.05

 

RPL7L1

2.47

1.54

1.17

 

RPS20

1.63

1.80

3.61*

 

ZNF777

-2.58

-2.23

-1.43

Cytoskeleton

FHDC1

-1.22

-1.45

-2.06

 

MYL3

-1.49

-1.62

-2.06

 

MYL5

-1.45

-1.69

-2.04

 

MYO1e

2.44

-1.05

NC

 

MYO9A

2.21

NC

NC

 

NAV1

1.42

1.45

2.11

 

PMFBP1

2.86

1.96

2.32

 

SORBS1

-1.22

-1.57

-2.20

 

ST3GAL5

2.07

1.87

1.96

 

SYNE2

-1.68

1.20

2.67

 

TM7

-1.17

-1.45

-2.10

 

TNNT3A

-1.17

-1.71

-2.01

Extracellular matrix

COL13A1

1.41

1.49

2.66

 

FGB

3.39*

1.63

1.14

 

FGG

4.64*

2.17

1.14

 

TINAG

-1.68

-2.01

-2.77

Metabolism

DAGLB

3.88*

1.26

1.49

 

DHRS4

4.45*

3.93*

4.21*

Cell protection

CYP2F1

-1.24

-1.55

-2.42

Degradation

TMPRSS9

-1.07

-1.70

-6.95*

Cell cycle

EVI5

4.00*

3.29*

3.85*

  1. Priority 1 and 2 proteins upregulated or downregulated by a value of 2.00 or more on one or more days post amputation (dpa). Asterisks indicate exceptionally high values (over 3.00) on one or more dpa.