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Table 1 Characteristics of CEACAM1-related genes of analyzed mammalian CEA families

From: Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families

abbreviation Latin name common name clade fold sequencing coverage CEACAM1-related genes
      total pseudo-genes GPI-liked members soluble members members with ITAM/ITAM-like motif members with ITIM/ITSM
Bta Bos taurus cattle laurasiatheria 7 6 1 0 1 0/2 0/1
Cfa Canis familiaris dog laurasiatheria 7.6 9 2 0 0 0/4 0/1
Cpo Cavia porcellus Guinea pig euarchontoglires 6.8 14 7 n.d. n.d. 0/1 1/1
Dno Dasypus novemcinctus armadillo xenarthra 2 10 0 n.d. 0 0/4 0/1
Eca Equus caballus horse laurasiatheria 7 27 13 0 7 0/1 0/2
Eeu Erinaceus europaeus hedgehog laurasiatheria 1.9 18 5 n.d. n.d. n.d n.d
Ete Echinops telfairi lesser hedgehog tenrec afrotheria 2 5 2 0 n.d. 0/1 n.d.
Fca Felis catus cat laurasiatheria 1.9 3 0 n.d. n.d. 0/1 0/1
Hsa Homo sapiens man euarchontoglires finished 29 11 4 10 0/2 1/0
Laf Loxodonto africana elephant afrotheria 2 8 0 n.d. n.d. 0/2 0/1
Mdo Monodelphis domestica opossum marsupialia 7.3 21 6 0 5 4/0 1/1
Meu Macropus eugenii tammar wallaby marsupialia 2 19 n.d. n.d. n.d. 4/0 0/0
Mlu Myotis lucifugus small brown bat laurasiatheria 1.7 >100 n.d. n.d. n.d. 0/1 1b
Mml Macaca mulatta rhesus macaque euarchontoglires 5.2 28 5 4 13 0/2 1/0
Mmu Mus musculus mouse euarchontoglires finished 28 1 0 24 0/0 0/2a
Mmr Microcebus murinus gray mouse lemur euarchontoglires 2 7 2 n.d. n.d. 0/1 0/1
Oan Ornithorhynchus anatinus platypus monotremata 6 5 0 n.d. n.d. n.d. 1/0
Ocu Oryctolagus cuniculus rabbit euarchontoglires 2 1 0 0 0 0/0 0/1
Oga Otolemur garnettii bush baby euarchontoglires 1.5 3 1 1 0 n.d. 0/1
Opr Ochotona princeps American pika euarchontoglires 1.9 2 1 n.d. n.d. n.d. 1b
Ppy Pongo pygmaeus orangutan euarchontoglires 7 28 11 4 9 0/2 1/0
Ptr Pan troglodytes chimpanzee euarchontoglires 6 27 11 4 9 0/2 1/0
Rno Rattus norvegicus rat euarchontoglires 11.9 18 0 0 14 0/0 0/1a
Sar Sorex araneus European shrew laurasiatheria 1.9 3 0 n.d. n.d. 0/1 1b
Str Spermophilus tridecemlineatus ground squirrel euarchontoglires 1.9 4 1 n.d. n.d. 0/1 0/1
Ssc Sus scrofa pig laurasiatheria 4 3 0 1 0 0/1 0/1
Tbe Tupaia belangeri tree shrew euarchontoglires 2 5 1 n.d n.d 0/1 0/1
  1. CEACAM gene identification in species with unfinished genome sequences are based partly on N domain exon counts. Genes were registered as pseudogenes when stop codons or frame shift mutations were detected in N domain exons. The number of members with ITAM or ITAM-like motifs and ITIM or ITSM are separated by slashes. For low coverage genome sequences gene numbers represent a minimal estimate.
  2. a allelic variants exist which were not taken into account; bneither classifiable as ITIM nor as ITSM (e.g. PxYxxI); n.d., not determined.