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Table 1 Characteristics of CEACAM1-related genes of analyzed mammalian CEA families

From: Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families

abbreviation

Latin name

common name

clade

fold sequencing coverage

CEACAM1-related genes

     

total

pseudo-genes

GPI-liked members

soluble members

members with ITAM/ITAM-like motif

members with ITIM/ITSM

Bta

Bos taurus

cattle

laurasiatheria

7

6

1

0

1

0/2

0/1

Cfa

Canis familiaris

dog

laurasiatheria

7.6

9

2

0

0

0/4

0/1

Cpo

Cavia porcellus

Guinea pig

euarchontoglires

6.8

14

7

n.d.

n.d.

0/1

1/1

Dno

Dasypus novemcinctus

armadillo

xenarthra

2

10

0

n.d.

0

0/4

0/1

Eca

Equus caballus

horse

laurasiatheria

7

27

13

0

7

0/1

0/2

Eeu

Erinaceus europaeus

hedgehog

laurasiatheria

1.9

18

5

n.d.

n.d.

n.d

n.d

Ete

Echinops telfairi

lesser hedgehog tenrec

afrotheria

2

5

2

0

n.d.

0/1

n.d.

Fca

Felis catus

cat

laurasiatheria

1.9

3

0

n.d.

n.d.

0/1

0/1

Hsa

Homo sapiens

man

euarchontoglires

finished

29

11

4

10

0/2

1/0

Laf

Loxodonto africana

elephant

afrotheria

2

8

0

n.d.

n.d.

0/2

0/1

Mdo

Monodelphis domestica

opossum

marsupialia

7.3

21

6

0

5

4/0

1/1

Meu

Macropus eugenii

tammar wallaby

marsupialia

2

19

n.d.

n.d.

n.d.

4/0

0/0

Mlu

Myotis lucifugus

small brown bat

laurasiatheria

1.7

>100

n.d.

n.d.

n.d.

0/1

1b

Mml

Macaca mulatta

rhesus macaque

euarchontoglires

5.2

28

5

4

13

0/2

1/0

Mmu

Mus musculus

mouse

euarchontoglires

finished

28

1

0

24

0/0

0/2a

Mmr

Microcebus murinus

gray mouse lemur

euarchontoglires

2

7

2

n.d.

n.d.

0/1

0/1

Oan

Ornithorhynchus anatinus

platypus

monotremata

6

5

0

n.d.

n.d.

n.d.

1/0

Ocu

Oryctolagus cuniculus

rabbit

euarchontoglires

2

1

0

0

0

0/0

0/1

Oga

Otolemur garnettii

bush baby

euarchontoglires

1.5

3

1

1

0

n.d.

0/1

Opr

Ochotona princeps

American pika

euarchontoglires

1.9

2

1

n.d.

n.d.

n.d.

1b

Ppy

Pongo pygmaeus

orangutan

euarchontoglires

7

28

11

4

9

0/2

1/0

Ptr

Pan troglodytes

chimpanzee

euarchontoglires

6

27

11

4

9

0/2

1/0

Rno

Rattus norvegicus

rat

euarchontoglires

11.9

18

0

0

14

0/0

0/1a

Sar

Sorex araneus

European shrew

laurasiatheria

1.9

3

0

n.d.

n.d.

0/1

1b

Str

Spermophilus tridecemlineatus

ground squirrel

euarchontoglires

1.9

4

1

n.d.

n.d.

0/1

0/1

Ssc

Sus scrofa

pig

laurasiatheria

4

3

0

1

0

0/1

0/1

Tbe

Tupaia belangeri

tree shrew

euarchontoglires

2

5

1

n.d

n.d

0/1

0/1

  1. CEACAM gene identification in species with unfinished genome sequences are based partly on N domain exon counts. Genes were registered as pseudogenes when stop codons or frame shift mutations were detected in N domain exons. The number of members with ITAM or ITAM-like motifs and ITIM or ITSM are separated by slashes. For low coverage genome sequences gene numbers represent a minimal estimate.
  2. a allelic variants exist which were not taken into account; bneither classifiable as ITIM nor as ITSM (e.g. PxYxxI); n.d., not determined.