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Figure 2 | BMC Biology

Figure 2

From: ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells

Figure 2

Art prevents chromosome instability in MSCs. (a) SKY analysis of wild type (WT) (top) or ArtΔ/Δ (bottom) mesenchymal stem cells (MSCs). An example of a chromatid break, typifying damage in ArtΔ/Δ cells, is indicated by an arrow and shown magnified. (b) Summary of spontaneous chromosomal abnormalities in WT versus ArtΔ/Δ. (c) Distribution of chromosome number in WT versus ArtΔ/Δ MSC karyotypes. Shown is the percentage of metaphase spreads from each karyotype harboring the indicated number of chromosomes.

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